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TranscriptomicsTranscription profiling of lamb Callipyge muscle types (ST, LD, SS, SM) at birth (T=0) and 12 weeks (T=12)
Microarrays were used for transcription profiling of skeletal muscle samples taken at birth, when the phenotype was not expressed, and 12 weeks of age from Callipyge and wild type sheep. The genes that underlie the expression of the phenotype rather than result from the fibre type change in the affe...
ORGANISM(S): Ovis aries 
2008-11-07 | E-GEOD-5955 | biostudies-arrayexpress
TranscriptomicsExpression data from Sheep kidney fat (KF) in lambs at 12 weeks of age; comparison of two genotypes, Callipyge (NCpat (CN)) and wild type (NN)
The ovine Callipyge mutation causes postnatal muscle hypertrophy localized to the pelvic limbs and torso, as well as body leanness. The mechanism underpinning enhanced muscle mass is unclear, as is the systemic impact of the mutation. Using muscle fibre typing immunohistochemistry we confirmed muscl...
ORGANISM(S): Ovis aries 
2014-06-03 | E-GEOD-58148 | biostudies-arrayexpress
TranscriptomicsAssessing the effect of the CLPG mutation on the microRNA catalogue of skeletal muscle using high-throughput sequencing
The callipyge phenotype is a monogenic muscular hypertrophy that is only expressed in heterozygous sheep receiving the CLPG mutation from their sire. The wild-type phenotype of CLPG/CLPG animals is thought to result from translational inhibition of paternally expressed DLK1 transcripts by maternally...
ORGANISM(S): Ovis aries 
2010-09-24 | E-GEOD-24146 | biostudies-arrayexpress
MetabolomicsImpacts of the Callipyge mutation on ovine plasma metabolites
The ovine Callipyge mutation causes postnatal muscle hypertrophy localized to the pelvic limbs and torso, as well as body leanness. The mechanism underpinning enhanced muscle mass is unclear, as is the systemic impact of the mutation. To investigate potential systemic effects of the mutation, 1H NMR...
2015-01-31 | MTBLS77 | MetaboLights
TranscriptomicsExpression data from Sheep longissimus dorsi (LD) muscle during development
Expression data from Sheep longissimus dorsi (LD) muscle during development; fetal lambs (80, 100, 120 days gestation), new born lambs at birth (150 d) and lambs at 12 weeks (230 d) The fetal to neonatal developmental transition corresponds with profound changes in skeletal muscle function as it a...
ORGANISM(S): Ovis aries 
2010-06-08 | E-GEOD-20112 | biostudies-arrayexpress
TranscriptomicsTranscriptome sequencing of Ovis aries
We have completed the high quality reference genome for domestic sheep (Oar v3.1) and performed a detailed survey of gene expression across different tissues. RNA-seq data of 7 tissue types from the reference female Texel and skin tissue from a Gansu alpine fine wool sheep were sequenced. Here is t...
ORGANISM(S): Ovis aries 
2014-06-06 | E-GEOD-56643 | biostudies-arrayexpress
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