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TranscriptomicsThe Multicopy Gene Sly Represses the Sex Chromosomes in the Male Mouse Germline after Meiosis
Studies of mice with Y chromosome long arm deficiencies suggest that the male-specific region (MSYq) encodes information required for sperm differentiation and postmeiotic sex chromatin repression (PSCR). Several genes have been identified on MSYq, but because they are present in more than 40 copies...
ORGANISM(S): Mus musculus 
2011-05-11 | E-GEOD-29198 | biostudies-arrayexpress
TranscriptomicsThe Multicopy Gene Sly Represses the Sex Chromosomes in the Male Mouse Germline after Meiosis part 2
Studies of mice with Y chromosome long arm deficiencies suggest that the male-specific region (MSYq) encodes information required for sperm differentiation and postmeiotic sex chromatin repression (PSCR). Several genes have been identified on MSYq, but because they are present in more than 40 copies...
ORGANISM(S): Mus musculus 
2011-05-11 | E-GEOD-29200 | biostudies-arrayexpress
TranscriptomicsDeficiency in the multicopy Sycp3-like X-linked genes Slx and Slxl1 causes major defects in spermatid differentiation
The gene Sly is present in multiple copies on the mouse Y chromosome and encodes a protein that is required for the epigenetic regulation of postmeiotic sex chromosome expression. The X chromosome carries two multicopy genes related to Sly: Slx and Slxl1. Here we investigate the role of Slx/Slxl1 us...
ORGANISM(S): Mus musculus 
2011-05-11 | E-GEOD-29197 | biostudies-arrayexpress
ProteomicsBoth L-lactyl and D-lactyl enantiomers modify histones in mouse testis
Dynamic histone post-translational modifications are crucial to precisely orchestrate gene expression programs. The recently discovered histone lysine lactylation has already been explored in various pathological contexts, but less in normal tissues. This modification exists as two enantiomers, L- a...
ORGANISM(S): Mus Musculus 
2026-06-23 | PXD070274 | panorama
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