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Genomics3D-printed wound dressings containing a fosmidomycin-derivative prevent Acinetobacter baumannii biofilm formation in vitro and in vivo
Two Acinetobacter baumannii strains with low susceptibility to fosmidomycin and two reference with high susceptibility to fosmidomycin were DNA-sequenced to investigate the genomic determinants of fosmidomycin resistance.
ORGANISM(S): Acinetobacter baumannii 
2022-12-21 | E-MTAB-12357 | biostudies-arrayexpress
GenomicsIdentification of adaptive mechanisms leading to reduced antibiotic susceptibility in bacterial biofilms using experimental evolution. Part 2: Burkholderia cenocepacia strain J2315 biofilms on beads
Burkholderia cenocepacia J2315 was repeatedly and intermittently exposed to tobramycin, ciprofloxacin or meropenem. Bacteria were grown on cryobeads submerged in liquid BHI medium. After 24 hours, the beads were washed and fresh medium with of without antibiotics added. After another 24 hours of inc...
ORGANISM(S): Burkholderia cenocepacia 
2022-08-18 | E-MTAB-12092 | biostudies-arrayexpress
GenomicsIdentification of adaptive mechanisms leading to reduced antibiotic susceptibility in bacterial biofilms using experimental evolution. Part 1: Pseudomonas aeruginosa strain AA2 biofilms on beads
Pseudomonas aeruginosa AA2 was repeatedly and intermittently exposed to tobramycin, ciprofloxacin or meropenem. Bacteria were grown on cryobeads submerged in liquid BHI medium. After 24 hours, the beads were washed and fresh medium with of without antibiotics added. After another 24 hours of incubat...
ORGANISM(S): Pseudomonas aeruginosa 
2022-08-18 | E-MTAB-12091 | biostudies-arrayexpress
GenomicsIdentification of adaptive mechanisms leading to reduced antibiotic susceptibility in bacterial biofilms using experimental evolution. Part 3: Pseudomonas aeruginosa floating biofilms in synthetic cystic fibrosis medium
Pseudomonas aeruginosa was repeatedly and intermittently exposed to tobramycin. Bacteria were grown in synthetic cystic fibrosis medium in wells of a 96-well microtiter plate. After 24 hours, more medium with or without tobramycin was added. After another 24 hours of incubation, a subsample of the w...
ORGANISM(S): Pseudomonas aeruginosa 
2022-08-18 | E-MTAB-11894 | biostudies-arrayexpress
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