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GenomicsHEB and E2A function as SMAD/FOXH1 cofactors
Nodal signaling, mediated through SMAD transcription factors, is necessary for pluripotency maintenance and endoderm commitment. We have identified a new motif, termed SMAD Complex Associated (SCA) that is bound by SMAD2/3/4 and FOXH1 in human embryonic stem cells (hESCs) and derived endoderm. We de...
ORGANISM(S): Xenopus (Silurana) tropicalis 
2011-08-23 | E-GEOD-30146 | biostudies-arrayexpress
GenomicsGenome-wide maps of REST and its cofactors in mouse E14 cells
We report the application of single-molecule-based sequencing technology for REST and its cofactors genome wide binding sites in E14 cells.We then combine these binding sirtes with REST regulating gene profiling, to understand REST binding and regulation in E14 cells. Examination of REST and 5 cofac...
ORGANISM(S): Mus musculus 
2011-04-01 | E-GEOD-28233 | biostudies-arrayexpress
GenomicsChIP-Seq for cofactors in cancer
Critical drivers of cancer progression are likely controlled through the actions of transcription factors and cofactors that bind to the genome and form enhancers that stimulate gene expression. We present ChIP-seq analysis of key transcriptional regulators, cofactors and histone modifications that...
ORGANISM(S): Homo sapiens 
2013-04-13 | E-GEOD-45984 | biostudies-arrayexpress
GenomicsTranscriptional cofactors display core promoter class-specificity
Transcriptional cofactors display core promoter class-specificity
PRJNA477764 | ENA
GenomicsTranscriptional cofactors display core promoter class-specificity in human
Transcriptional cofactors display core promoter class-specificity in human
PRJNA521352 | ENA
GenomicsChIP-Seq for cofactors in cancer
Critical drivers of cancer progression are likely controlled through the actions of transcription factors and cofactors that bind to the genome and form enhancers that stimulate gene expression. We present ChIP-seq analysis of key transcriptional regulators, cofactors and histone modifications that ...
ORGANISM(S): Homo sapiens 
2013-04-13 | GSE45984 | GEO
GenomicsDietary folate and cofactors accelerate age-dependent p16 epimutation to promote intestinal tumorigenesis
Dietary folate and cofactors accelerate age-dependent p16 epimutation to promote intestinal tumorigenesis
PRJNA1019771 | ENA
UnknownThe CoFactor database: organic cofactors in enzyme catalysis.
Not available
S-EPMC2944199 | biostudies-literature
GenomicsSeparable roles for Microprocessor and its cofactors ERH and SAFB1/2 during microRNA cluster assistance
Separable roles for Microprocessor and its cofactors ERH and SAFB1/2 during microRNA cluster assistance
PRJEB101478 | ENA
GenomicsRoles of Cofactors and Chromatin Accessibility in Hox Protein Target Specificity
Regulation of specific target genes by transcription factors is central to gene network control in development. How target specificity is achieved in eukaryotic genomes is poorly understood, as exemplified by the Hox family, which show limited in vitro DNA-binding specificity but clear functional sp...
ORGANISM(S): Drosophila melanogaster 
2015-12-07 | E-GEOD-69796 | biostudies-arrayexpress
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