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MetabolomicsFrailty markers comprise blood metabolites involved in antioxidation, cognition, and mobility
As human society ages globally, age-related disorders are becoming increasingly common. Due to decreasing physiological reserves and increasing organ system dysfunction associated with age, frailty affects many elderly people, compromising their ability to cope with acute stressors. Frail elderly pe...
2020-05-01 | MTBLS1540 | MetaboLights
MetabolomicsMicrobiota network modules-derived tryptophan metabolites improve cognition via microglial AhR/Sirpα signaling

Gut microbiota dysbiosis has emerged as one of the hallmarks of aging, highlighting the need to identify microbial network modules as new biomarkers rooted in microbiota interactions and develop targeted nutritional interventions. The current research, integrating data from Alzheimer's disease (A...

2026-08-08 | MTBLS12506 | MetaboLights
MetabolomicsMicrobiota network modules-derived tryptophan metabolites improve cognition via microglial AhR/Sirpα signaling

Gut microbiota dysbiosis has emerged as one of the hallmarks of aging, highlighting the need to identify microbial network modules as new biomarkers rooted in microbiota interactions and develop targeted nutritional interventions. The current research, integrating data from Alzheimer's disease (A...

2026-08-08 | MTBLS12508 | MetaboLights
MetabolomicsHabitual Coffee Intake Shapes the Gut Microbiome and Modifies Host Physiology and Cognition

Coffee influences multiple physiological processes, including gut function, stress, cognition, and the microbiome. However, the mechanisms underlying these effects remain poorly understood. In this study, we examined coffee’s impact on the microbiota–gut–brain axis—a bidirectional communication p...

2026-04-07 | MTBLS13494 | MetaboLights
MetabolomicsMicrobiota network modules-derived tryptophan metabolites improve cognition via microglial AhR/Sirpα signaling
Gut microbiota dysbiosis has emerged as one of the hallmarks of aging, highlighting the need to identify microbial network modules as new biomarkers rooted in microbiota interactions and develop targeted nutritional interventions. The current research, integrating data from Alzheimer's disease (AD) ...
2026-08-07 | MTBLS15265 | MetaboLights
ProteomicsChanges in Gut, Microbiome, and Cognition after Doxorubicin, Cyclophosphamide, and Paclitaxel Chemotherapy Treatment
Correlating changes in inflammatory markers in the intestine with alterations in cognition and the gut microbiome after chemotherapy treatment.
ORGANISM(S): Mus musculus (Mouse) 
2025-09-12 | PXD063819 | Pride
Doxorubicin Intestine Hippocampal Microbiome Cyclophosphamide Cognition Paclitaxel Proteomics 
UnknownCall to action on social cognition measures in clinical research.
Not available
S-EPMC12661152 | biostudies-literature
TranscriptomicsChanges in mouse cognition and hippocampal gene expression observed in a mild physical- and blast-traumatic brain injury
Warfare has long been associated with traumatic brain injury (TBI) in militarized zones. Common forms of TBI can be caused by a physical insult to the head-brain or by the effects of a high velocity blast shock wave generated by the detonation of an explosive device. While both forms of trauma are d...
ORGANISM(S): Mus musculus 
2013-03-18 | E-GEOD-44625 | biostudies-arrayexpress
UnknownRethinking raptors: caracaras as a model for avian cognition in the wild.
Not available
S-EPMC12575590 | biostudies-literature
GenomicsEffect of gut microbiome modulation on muscle function and cognition: the PROMOTe randomised controlled trial
Prebiotic intervention for muscle function and cognition
PRJEB72531 | ENA
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