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We study the effect of four QTN in RME1, IME1 & RSF1 that are causative for variation in sporulation efficiency. We investigate the relationship between genotype, gene expression and phenotype and whether the amount of gene expression variation explained by the sporulation QTN is predictive of the a...
ORGANISM(S): Saccharomyces cerevisiae 
Acquiring new cellular states entails metabolic reprogramming driven by adjustments to the expression of metabolic enzymes in the cytosol and mitochondria. Most mitochondrial proteins are synthesized in the cytosol and imported into the mitochondria in a linear form, after which they are folded by a...
ORGANISM(S): Homo sapiens (Human) 
2026-10-05 | PXD066753 | Pride
The cell-free biogenesis of the protein translation machinery is essential for the creation of a self-regenerating synthetic cell. Here, we demonstrate the autonomous and simultaneous biogenesis of all thirty proteins of the translation machinery of E. coli in a reconstituted transcription-translati...
ORGANISM(S): Escherichia coli 
2025-12-09 | PXD071320 | Pride
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