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TranscriptomicsTranscription profiling of human low gestational age newborns as predictors of bronchopleural pulmonary dysplasia
One third to one half of all infants born before the 28th wek of gestation develop BPD bronchopulmonary dysplasia. Our objective is to evaluate the feasibility of using expression profiling in umbilical cord tissue to discover molecular signatures for developmental staging and for risk of BPD. Expe...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8586 | biostudies-arrayexpress
UnknownSafety and survival with GVAX pancreas prime and Listeria Monocytogenes-expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer.
Not available
S-EPMC4397277 | biostudies-literature
UnknownRepeat tick exposure elicits distinct immune responses in guinea pigs and mice.
Not available
S-EPMC7530331 | biostudies-literature
MetabolomicsNQO1 protects obese mice through improvements in glucose and lipid metabolism.
Chronic nutrient excess leads to metabolic disorders and insulin resistance. Activation of stress-responsive pathways via Nrf2 activation contributes to energy metabolism regulation. Here, inducible activation of Nrf2 in mice and transgenesis of the Nrf2 target, NQO1, conferred protection from diet-...
2024-05-23 | MTBLS2085 | MetaboLights
UnknownThe bii4africa dataset of faunal and floral population intactness estimates across Africa's major land uses.
Not available
S-EPMC10861571 | biostudies-literature
UnknownTaking Innovation To Scale In Primary Care Practices: The Functions Of Health Care Extension.
Not available
S-EPMC5805471 | biostudies-literature
TranscriptomicsMOTS-c: A Novel Peptide Encoded by a Short Mitochondrial Open Reading Frame Regulates Metabolic Homeostasis
Mitochondria are known to be functional organelles, but their role as a signaling unit is increasingly being appreciated. The recent identification of a short open reading frame (sORF) in the mitochondrial DNA (mtDNA) that encodes a signaling peptide, humanin, suggests the possible existence of addi...
ORGANISM(S): Homo sapiens 
2015-03-07 | E-GEOD-65068 | biostudies-arrayexpress
TranscriptomicsDamID (LmnB1/Dam) Log2 ratios of C57Bl/6 fibroblasts and RAG2-/- pro-B cells.
Comparison of DamID profiles and LAD patterning across cell types reveals regions of variable LADs LmnB1 interactions at the nuclear periphery of C57Bl/6 pro-B cells and fibroblasts were identified by DamID in duplicate for both pro-B and fibroblasts (4 samples total). For each sample, Dam-LmnB1/Dam...
ORGANISM(S): Mus musculus 
2014-12-16 | E-GEOD-56990 | biostudies-arrayexpress
UnknownSustained CD28 costimulation is required for self-renewal and differentiation of TCF-1+ PD-1+ CD8 T cells.
Not available
S-EPMC10805182 | biostudies-literature
ProteomicsQuantitative Measurement of the Requirement of Diverse Protein Degradation Pathways in MHC Class I Peptide Presentation
The adaptive immune system distinguishes self from non-self by surveying peptides generated from degradation of intracellular proteins that are loaded onto MHC Class I molecules for display on the cell surface. While early studies reported that the bulk of cell surface MHC Class I complexes require ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-02-15 | MSV000091285 | MassIVE
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