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ProteomicsSite-Specific Ubiquitination of Pathogenic Huntingtin Attenuates its Deleterious Effects
Huntington’s disease (HD) is a progressive incurable neurodegenerative disorder characterized by motor and neuropsychiatric symptoms. It is caused by expansion of a CAG triplet in the N-terminal domain of exon 1 in the huntingtin (HTT) gene that codes for an expanded polyglutamine (polyQ) stretch in...
ORGANISM(S): Rattus rattus (Black rat) 
2020-06-30 | PXD019553 | Pride
Huntingtin ubiquitination 
ProteomicsSite-Specific Ubiquitination of Pathogenic Huntingtin Attenuates its Deleterious Effects- PART2
Huntington’s disease (HD) is a progressive incurable neurodegenerative disorder characterized by motor and neuropsychiatric symptoms. It is caused by expansion of a CAG triplet in the N-terminal domain of exon 1 in the huntingtin (HTT) gene that codes for an expanded polyglutamine (polyQ) stretch in...
ORGANISM(S): Homo sapiens (Human) 
2020-06-30 | PXD019552 | Pride
Ubiquitination huntingtin 
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