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ModelsChaouiya2013 - EGF and TNFalpha mediated signalling pathway
Chaouiya2013 - EGF and TNFalpha mediated signalling pathway This model is described in the article: SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools. Chaouiya C, Bérenguier D...
2024-09-02 | BIOMD0000000562 | BioModels
TranscriptomicsComparative transcriptomic responses of bank vole kidney and respiratory epithelial cells to distinct orthohantaviruses
Orthohantaviruses are rodent-borne viruses that can cause severe disease in humans but remain asymptomatic in their natural hosts. Increasing outbreaks and ecological changes raise important public health concerns. Understanding how these viruses interact with host cells is essential, particularly i...
ORGANISM(S): Myodes glareolus 
2026-06-15 | E-MTAB-16656 | biostudies-arrayexpress
GenomicsCCR5 HIV controllers
Sequencing of 9kb of the CCR5 genomic locus in 15 patients who naturally control HIV infection
ORGANISM(S): Homo sapiens 
2021-12-07 | E-MTAB-11062 | biostudies-arrayexpress
TranscriptomicsJC polyomavirus whole genome sequencing at the single molecule level reveals emerging viral populations in Progressive Multifocal Leucoencephalopathy
JC polyomavirus (circular genome) contains two opposite coding regions separated by the regulator non-coding control region (NCCR). NCCR rearrangements and missense mutations in the viral capsid protein VP1 gene differentiate JCV prototype genomes recovered from PML lesions from archetype urine stra...
ORGANISM(S): JC polyomavirus 
2022-01-12 | E-MTAB-11077 | biostudies-arrayexpress
GenomicsCapturing SARS-cov in low abundant patient samples: a comparative analysis (twist panviral NS).
In this study, we tested the efficacy of five commercial probes panels at detecting SARS-CoV-2 genome including panels from Illumina, Twist Bioscience and Arbor Bioscience. To do so, we used 19 patient nasal swab samples broken down into 5 series of 4 samples of equivalent SARS-CoV-2 viral load (cyc...
ORGANISM(S): Homo sapiens 
2022-06-01 | E-MTAB-11237 | biostudies-arrayexpress
TranscriptomicsIntrinsic Differences in Hamster and Mouse Macrophages Biology
Hamster (ham) and mouse (m) bone marrow-derived macrophages (BMDMs) exhibit differential susceptibility to microbial infections, including Leishmania donovani. We hypothesize that intrinsic biological differences between these rodent macrophages contribute to this variability and ultimately to disea...
ORGANISM(S): Mus musculus 
2026-05-14 | E-MTAB-15420 | biostudies-arrayexpress
TranscriptomicsBile-induced biofilm formation in Bacteroides thetaiotaomicron requires magnesium efflux by an RND pump
The study is about the role of Bacteroides thetaiotaomicron in the human gut microbiota, specifically its ability to form biofilms in response to bile salts. The study found that bile induces the expression of certain efflux pumps, and inhibiting these pumps impairs biofilm formation. Among the indu...
ORGANISM(S): Bacteroides thetaiotaomicron 
2024-03-19 | E-MTAB-13460 | biostudies-arrayexpress
OtherPhosphoproteomic analyses reveal novel cross-modulation mechanisms between two signaling pathways in yeast.
Data from ProteomeXchange, PXD ID: PXD001445. File: vagas_O1210_369.c.mzXML. Published as part of Mol Syst Biol. 2014 Dec 9;10(12):767 . From the Abstract: {{i}} Cells respond to environmental stimuli via specialized signaling pathways. Concurrent stimuli trigger multiple pathways that integrate in...
ORGANISM(S): Yeast 
GPM32320005651 | GPMDB
Resource Reanalysis 
TranscriptomicsEvaluation of methods for modeling transcription factor sequence specificity
Genomic analyses often involve scanning for potential transcription-factor (TF) binding sites using models of the sequence specificity of DNA binding proteins. Many approaches have been developed to model and learn a protein’s binding specificity by representing sequence motifs, including the gaps a...
ORGANISM(S): synthetic construct 
2012-12-13 | E-GEOD-42864 | biostudies-arrayexpress
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