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MetabolomicsNQO1 protects obese mice through improvements in glucose and lipid metabolism.
Chronic nutrient excess leads to metabolic disorders and insulin resistance. Activation of stress-responsive pathways via Nrf2 activation contributes to energy metabolism regulation. Here, inducible activation of Nrf2 in mice and transgenesis of the Nrf2 target, NQO1, conferred protection from diet-...
2024-05-23 | MTBLS2085 | MetaboLights
GenomicsGenome-wide nucleosome maps for wild type and Rsc8-depleted Saccharomyces cerevisiae
Paired-end sequencing study of nucleosomes from MNase-digested nuclei. Nucleosomal DNA from wild type and Rsc8-depleted cells was subjected to paired-end sequencing.
ORGANISM(S): Saccharomyces cerevisiae 
2014-06-11 | E-GEOD-49512 | biostudies-arrayexpress
UnknownAutomated Adaptive Absolute Binding Free Energy Calculations.
Not available
S-EPMC11428140 | biostudies-literature
UnknownComparison of Receptor-Ligand Restraint Schemes for Alchemical Absolute Binding Free Energy Calculations.
Not available
S-EPMC10308817 | biostudies-literature
TranscriptomicsTranscriptional profiling of primary human alveolar macrophages challenged with Streptococcus pneumoniae from patients with chronic obstructive pulmonary disease compared to healthy donors
Transcriptional profiling of primary human alveolar macrophages (AMs) comparing control untreated AMs with AMs exposed with Serotype 14 Streptococcus pneumoniae (NCTC11902) strain (MOI 10) for 4 hours) Two-condition experiment, control AMs vs. infected AMs. Biological replicates: 3 control replicat...
ORGANISM(S): Homo sapiens 
2018-02-26 | E-MTAB-6491 | biostudies-arrayexpress
UnknownEvidence of complement dysregulation in outer retina of Stargardt disease donor eyes.
Not available
S-EPMC7767765 | biostudies-literature
UnknownC-terminal turn stability determines assembly differences between Aβ40 and Aβ42.
Not available
S-EPMC3540122 | biostudies-literature
UnknownA small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model.
Not available
S-EPMC6279743 | biostudies-literature
UnknownPreliminary evaluation of a mindfulness intervention program in women with long COVID dysautonomia symptoms.
Not available
S-EPMC11879682 | biostudies-literature
UnknownSelective Inhibition of Nuclear Export With Oral Selinexor for Treatment of Relapsed or Refractory Multiple Myeloma.
Not available
S-EPMC6905485 | biostudies-literature
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