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MetabolomicsInhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells

BACKGROUND: Neuroblastoma accounts for 7% of paediatric malignancies but is responsible for 15% of all childhood cancer deaths. Despite rigorous treatment involving chemotherapy, surgery, radiotherapy and immunotherapy, the 5-year overall survival rate of high-risk disease remai...

2022-11-30 | MTBLS858 | MetaboLights
UnknownBRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group.
Not available
S-EPMC3413277 | biostudies-literature
TranscriptomicsTranscription profiling of mouse colon response to quercetin in WT and POR-null animals
Using mice deficient in hepatic cytochrome-P450 oxidoreductase (POR), which disables the liver cytochrome P450 system, the metabolism and biological response of the anti-carcinogenic flavonoid, quercetin, was examined. Profiling circulating metabolites revealed similar profiles over 72 h in wild typ...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-4256 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver response to quercetin in WT and POR-null mice
Using mice deficient in hepatic cytochrome-P450 oxidoreductase (POR), which disables the liver cytochrome P450 system, the metabolism and biological response of the anti-carcinogenic flavonoid, quercetin, was examined. Profiling circulating metabolites revealed similar profiles over 72 h in wild typ...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-4259 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse ileum response to quercetin in WT and POR-null mice
Using mice deficient in hepatic cytochrome-P450 oxidoreductase (POR), which disables the liver cytochrome P450 system, the metabolism and biological response of the anti-carcinogenic flavonoid, quercetin, was examined. Profiling circulating metabolites revealed similar profiles over 72 h in wild typ...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-4257 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse POR-null and wild type jejunum response to quercetin
Using mice deficient in hepatic cytochrome-P450 oxidoreductase (POR), which disables the liver cytochrome P450 system, the metabolism and biological response of the anti-carcinogenic flavonoid, quercetin, was examined. Profiling circulating metabolites revealed similar profiles over 72 h in wild typ...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-4258 | biostudies-arrayexpress
TranscriptomicsBenzo-a-pyrene induced miRNA changes in mouse
Mice were applied with 125mg/day/kg body weight for 5 days while control mice were applied with corn oil. The microRNA expression profiles of 3 target organs (lung, spleen and forestomach) and 3 non-target organs (liver, colon and glandular stomach) were compared to look for the difference betwee...
ORGANISM(S): Mus musculus 
2014-06-30 | E-MTAB-2407 | biostudies-arrayexpress
UnknownCombined Microsatellite Instability, MLH1 Methylation Analysis, and Immunohistochemistry for Lynch Syndrome Screening in Endometrial Cancers From GOG210: An NRG Oncology and Gynecologic Oncology Group Study.
Not available
S-EPMC4678181 | biostudies-literature
TranscriptomicsTranscription profiling of mouse organs after treatment with benzo-a-pyrene
Not available
ORGANISM(S): Mus musculus 
2012-06-01 | E-MTAB-80 | biostudies-arrayexpress
GenomicsCRUK-ICGC Prostate Cancer Group Study
Prostate cancer somatic genomic sequencing data generated from 2011 onwards under auspices of the International Cancer Genome Consortium Prostate Cancer UK consortium (CRUK-ICGC Prostate Group), co-led by Colin Cooper and Ros Eeles, with other Principal Investigators (Brewer, Neal, Bova, McDermott, ...
EGAS00001000262 | EGA
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