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Although the gut microbiome plays important roles in host physiology, health and disease, we lack understanding of the complex interplay between host genetics and early life environment on the microbial and metabolic composition of the gut. We used the genetically diverse Collaborative Cross mouse s...
2016-10-05 | MTBLS345 | MetaboLights
RNA-Seq was performed on all 8 mouse founder strains of the Collaborative Cross to obtain a comprehensive splicing landscape of each strain.
ORGANISM(S): Mus musculus 
Whole-genome sequencing of mouse recombinant inbred lines from the Collaborative Cross panel.
Collaborative Cross (CC) mouse embryonic fiborolasts (MEF) cells obtained from the eight Founder animals [PWK/PhJ, NZO/HILtJ, NOD/ShiLtJ, WSB/EiJ, A/J, CAST, C57BL/6J, and 129/SvlmJ] were immortalized and the cell lines used to assess differences in transcriptional responses following treatment with...
ORGANISM(S): Mus musculus 
The Collaborative Cross (CC) recombinant inbred panel was conceived as an ideal resource for mammalian system genetics. The pre-CC is a proof-of-concept experiment involving CC lines that have undergone at least five generations of inbreeding. Siblings from these lines were each involved in one of f...
ORGANISM(S): Mus musculus 
Whole genome sequencing and progress towards full inbreeding of the mouse Collaborative Cross population
The data was used for eQTL analysis of cecum gene expression in the Collaborative Cross Breeding Population.
ORGANISM(S): Mus musculus 
2018-07-01 | GSE96924 | GEO
The goal of this project was to identify strain-dependent expression of miRNAs in lung tissue from Collaborative Cross founder strains that were sensitized and challenged with house dust mite allergen (Der p 1). We analyzed whole lung RNAs from the eight Collaborative Cross founder strains (n=4/stra...
ORGANISM(S): Mus musculus 
Collaborative Cross (CC) mouse embryonic fibroblasts (MEF) cells obtained from the eight Founder animals [PWK/PhJ, NZO/HILtJ, NOD/ShiLtJ, WSB/EiJ, A/J, CAST, C57BL/6J, and 129/SvlmJ] were immortalized and the cell lines used to assess differences in transcriptional responses following treatment with...
ORGANISM(S): Mus musculus 
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