Sort   by:  
 Page size 
TranscriptomicsHow C/EBPa creates an elite cell state for reprogramming to pluripotency
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-02-19 | E-GEOD-71218 | biostudies-arrayexpress
GenomicsHow C/EBPa creates an elite cell state for reprogramming to pluripotency [ChIPseq]
Mouse Bcell, upon ectopic expression of the transcription factor Cebpa for 18h, can be reprogrammed to iPS with extremely high efficiency. To understand the molecular control of this phenomena we performed multiple high throughtput functionnal genomic analysis. Genome binding/occupancy of transcript...
ORGANISM(S): Mus musculus 
2016-02-19 | E-GEOD-71215 | biostudies-arrayexpress
TranscriptomicsHow C/EBPa creates an elite cell state for reprogramming to pluripotency [ATACseq]
Mouse Bcell, upon ectopic expression of the transcription factor Cebpa for 18h, can be reprogrammed to iPS with extremely high efficiency. To understand the molecular control of this phenomena we performed multiple high throughtput functionnal genomic analysis. Chromatin accessibility by ATACseq in ...
ORGANISM(S): Mus musculus 
2016-02-19 | E-GEOD-71214 | biostudies-arrayexpress
TranscriptomicsHow C/EBPa creates an elite cell state for reprogramming to pluripotency [array]
Mouse Bcell, upon ectopic expression of the transcription factor Cebpa for 18h, can be reprogrammed to iPS with extremely high efficiency. To understand the molecular control of this phenomena we performed multiple high throughtput functional genomic analysis. Transcriptomic by microarray in Bcell, ...
ORGANISM(S): Mus musculus 
2016-02-19 | E-GEOD-71213 | biostudies-arrayexpress
TranscriptomicsHow C/EBPa creates an elite cell state for reprogramming to pluripotency [RNAseq]
Mouse Bcell, upon ectopic expression of the transcription factor Cebpa for 18h, can be reprogrammed to iPS with extremely high efficiency. To understand the molecular control of this phenomena we performed multiple high throughtput functionnal genomic analysis. Transcriptomic by RNAseqencing (polyA+...
ORGANISM(S): Mus musculus 
2016-02-19 | E-GEOD-71217 | biostudies-arrayexpress
TranscriptomicsHow C/EBPa creates an elite cell state for reprogramming to pluripotency [4C]
Mouse Bcell, upon ectopic expression of the transcription factor Cebpa for 18h, can be reprogrammed to iPS with extremely high efficiency. To understand the molecular control of this phenomena we performed multiple high throughtput functionnal genomic analysis. Circularized chromosome conformation c...
ORGANISM(S): Mus musculus 
2016-02-19 | E-GEOD-75481 | biostudies-arrayexpress
GenomicsGenome-wide maps of chromatin states during B-cell to Macrophage lineage switching
Using homogenous populations of cells undergoing lineage switching we studied enhancer nucleation. Examination of 3 histone marks several time points after induction of transdifferentiation
ORGANISM(S): Mus musculus 
2015-07-29 | E-GEOD-53173 | biostudies-arrayexpress
GenomicsGenome-wide maps of transcription factor and co-factor binding during B-cell to Macrophage lineage switching
Using homogenous populations of cells undergoing cell switching we observed an interplay between lymphoid and myeloid transcription factors during lineage switching Examination of transcription factors genome-wide binding profiles several time points after induction of B-cell to macrophage lineage s...
ORGANISM(S): Mus musculus 
2015-07-29 | E-GEOD-53362 | biostudies-arrayexpress
GenomicsNucleosome density map during B-cell to Macrophage lineage switching
Using homogenous populations of cells undergoing lineage switching we studied enhancer nucleation related to nucleosme organization. Examination of nucleosome densities by using Mnase-seq at several time points after induction of lineage switching
ORGANISM(S): Mus musculus 
2015-07-29 | E-GEOD-53460 | biostudies-arrayexpress
Models,MultiomicsLymphoid and myeloid cell specification and transdifferentiation
Blood cells are derived from a common set of hematopoietic stem cells, which differentiate into more specific progenitors of the myeloid and lymphoid lineages, ultimately leading to differentiated cells. This developmental process is controlled by a complex regulatory network involving cytokines and...
8186 | Cell Collective
Sort   by:  
 Page size