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We compared transcriptomic profiles of 23 ICC tumor specimens to hepatocellular carcinoma (HCC) specimens using Affymetrix mRNA array and the miRNA array platforms to search for unique gene signatures linked to patient prognosis. ICC and HCC share common stem-like molecular characteristics and stem-...
ORGANISM(S): Homo sapiens 
The heterogeneity analysis of hepatocellular carcinoma and combined hepatocellular cholangiocarcinoma
We performed genomic and transcriptomic sequencing of 133 combined hepatocellular and intrahepatic cholangiocarcinoma (cHCC-ICC) cases, including separate, combined, and mixed subtypes.
We performed gene expression profiling of hepatocellular carcinoma (HCC), cholangiocarcinoma (CC), and mixed type of combined HCC and CC (CHC). In comparison of the profiles, a novel class of HCC expressing CC-like traits was identified. Gene expression profiling of 70 hepatocellular carcinoma (HCC)...
ORGANISM(S): Homo sapiens 
Spatial transcriptome on human combined hepatocellular cholangiocarcinoma
We compared transcriptomic profiles of ICC tumor specimens to hepatocellular carcinoma (HCC) specimens using Affymetrix mRNA array and the miRNA array platforms to search for unique gene signatures linked to patient prognosis. ICC and HCC share common stem-like molecular characteristics and stem-lik...
ORGANISM(S): Homo sapiens 
To investigate the molecular heterogeneity of hepatocellular carcinoma (HCC) and combined hepatocellular cholangiocarcinoma (cHCC-CCA) , we then performed gene expression profiling analysis using data obtained from RNA-seq of 81 patients with HCC and cHCC-CCA.
ORGANISM(S): Homo sapiens 
2026-04-30 | GSE231854 | GEO
Comprehensive Molecular Profiling of Combined Hepatocellular Carcinoma and Cholangiocarcinoma reveals Distinct Notch Signaling Subgroups with Prognostic Significance
Using single-cell RNA sequencing, spatial transcriptomic and bulk multi-omics, we elaborated a molecular architecture of 3 PLC types, namely hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and combined hepatocellular-cholangiocarcinoma (CHC) from a high-resolution perspective.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD044778 | Pride
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