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Gut complement induced by the microbiota combats pathogens and spares commensals
Gut complement induced by the microbiota combats pathogens and spares commensals
Plants are colonized by a variety of microorganisms, the plant microbiota. In the phyllosphere, the above-ground parts of plants, bacteria are the most abundant inhabitants. Most of these microorganisms are not pathogenic and the plant responses to commensals or to pathogen infection in the presence...
ORGANISM(S): Arabidopsis thaliana 
Canonically, the complement system is known for its rapid response to remove microbes in the bloodstream. However, relatively little is known about a functioning complement system on intestinal mucosal surfaces. Herein we report the local synthesis of complement component 3 (C3) in the gut, primaril...
ORGANISM(S): Mus musculus 
2024-01-16 | GSE250268 | GEO
Canonically, the complement system is known for its rapid response to remove microbes in the bloodstream. However, relatively little is known about a functioning complement system on intestinal mucosal surfaces. Herein we report the local synthesis of complement component 3 (C3) in the gut, primaril...
ORGANISM(S): Mus musculus 
2023-12-04 | GSE248940 | GEO
M cells are the main site of bacterial translocation in the intestine. We used the in vitro M cell model to study the effect of the commensal bacteria; Lactobacillus salivarius, Eschericha coli and Bacteroides fragilis, on M cell gene expression. Bacterial translocation across the gut mucosa has tra...
ORGANISM(S): Homo sapiens 
Neisseria commensals from Japan 2025
The intestinal microbiota fundamentally influences the development of a normal intestinal physiology and education and functioning of the mucosal immune system. Using the C. rodentium carrier model of germfree mice (GF), we found that colonization of adult GF with 14 selected commensals (OMM12+MC2) ...
ORGANISM(S): Mus musculus 
2021-09-09 | GSE180156 | GEO
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