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MetabolomicsCommunity metabolomics provides insights into mechanisms of pollution-induced community tolerance of periphyton

Chemical pollution is a major concern for freshwater ecosystems, but the impact and mechanisms of chemical stressors on communities are barely understood. Pollution stress beyond natural homeostatic capacities can trigger succession of tolerant species within a community, enhancing the overall co...

2022-02-11 | MTBLS3595 | MetaboLights
MetabolomicsMicrobial community functioning during plant litter decomposition

Microbial life in soil is fueled by dissolved organic matter (DOM) that leaches from the litter layer. It is well known that decomposer communities adapt to the available litter source, but it remains unclear if they functionally compete or synergistically address different litter types. Therefor...

2024-02-14 | MTBLS1885 | MetaboLights
MetabolomicsConsistency across multi-omics layers in a drug-perturbed gut microbial community
Multi-omics analyses are increasingly employed in microbiome studies to obtain a holistic view of molecular changes occurring within microbial communities exposed to different conditions. However, it is not always clear to what extent each omics data type contributes to our understanding of the comm...
2022-12-08 | MTBLS3129 | MetaboLights
MetabolomicsA synthetic community system for probing microbial interactions driven by exometabolites
Despite that most microorganisms live as part of community, we have modest knowledge about the interactions among microbial community members in nature, and the implications of those interactions for emergent community properties or ecosystem-relevant functions. To facilitate advances in understandi...
2017-10-26 | MTBLS525 | MetaboLights
MetabolomicsArbuscular mycorrhizal fungi-mediated differential composition and metabolism of rhizosphere microbial community

Arbuscular mycorrhizal fungi-mediated differential composition and metabolism of rhizosphere microbial community. Using Syncoms containg Rhizophagus intraradices, Nigrospora oryzae and Talaromyces verruculosus.

2024-07-29 | MTBLS7299 | MetaboLights
MetabolomicsA defined community of core gut microbiota members promotes cognitive performance in honey bees

Gut microbiota across animals have been shown to influence host cognition and behavior. However, it remains unclear whether these cognitive effects are driven by specific bacterial species or arise from community-level interactions. Here, we leveraged the honey bee (Apis mellifera) as a ...

2026-05-21 | MTBLS13943 | MetaboLights
MetabolomicsLipid metabolites as potential diagnostic and prognostic biomarkers for acute community acquired pneumonia
Early diagnosis of acute community-acquired pneumonia (CAP) is important in patient triage and treatment decisions. To identify biomarkers that distinguish patients with CAP from non-CAP controls, we conducted an untargeted global metabolome analysis for plasma samples from142 patients with CAP (CAP...
2016-08-11 | MTBLS354 | MetaboLights
MetabolomicsOceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges
Marine sponges (phylum Porifera) are leading organisms for the discovery of bioactive compounds from nature. Their often rich and species-specific microbiota is hypothesised to be producing many of these compounds. Yet, environmental influences on the sponge-associated microbiota and bioactive compo...
2023-05-12 | MTBLS1388 | MetaboLights
MetabolomicsMetabolic network construction reveals probiotic-specific colonization resistance in a synthetic small intestinal community

The gut microbiota is essential to host health. Probiotics can be used as a microbiota targeted therapy to improve host health. However, probiotic molecular mechanisms of action and probiotics targeting the small intestinal microbiota are often not elucidated. In this study, we construct a three ...

2024-09-26 | MTBLS7370 | MetaboLights
MetabolomicsDiel metabolomics analysis of a hot spring chlorophototrophic microbial mat leads to new hypotheses of community member metabolisms
Dynamic environmental factors such as light, nutrients, salt, and temperature continuously affect chlorophototrophic microbial mats, requiring adaptive and acclimative responses to stabilize composition and function. Quantitative metabolomics analysis can provide insights into metabolite dynamics fo...
2024-02-23 | MTBLS187 | MetaboLights
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