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MetabolomicsMacrophage-mediated antibiotic evasion and competitive dominance of mcr-3-carrying Escherichia coli

Mobile colistin resistance (mcr) genes undermine the efficacy of last-line polymyxin antibiotics, and the global prevalence of mcr-3 continues to rise despite reduced colistin use. Here, we show that mcr-3-positive Escherichia coli (E. coli) confers a survival advantage by reprogramming macrophag...

2026-05-30 | MTBLS13550 | MetaboLights
GenomicsMetformin reduces the competitive advantage of Dnmt3aR878H HSPCs
Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs
PRJNA1073514 | ENA
GenomicsMetformin reduces the competitive advantage of Dnmt3aR878H HSPCs [BulkRNA]
Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs [BulkRNA]
PRJNA1073519 | ENA
GenomicsMetformin reduces the competitive advantage of Dnmt3aR878H HSPCs [RRBS]
Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs [RRBS]
PRJNA1076523 | ENA
GenomicsMetformin reduces the competitive advantage of Dnmt3aR878H HSPCs [ChIP-Seq]
Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs [ChIP-Seq]
PRJNA1075428 | ENA
GenomicsMetformin reduces the competitive advantage of Dnmt3aR878H HSPCs [CITE-Seq]
Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs [CITE-Seq]
PRJNA1072018 | ENA
GenomicsTET2 Deficiency Increases the Competitive Advantage of Hematopoietic Stem Cells through Upregulation of Thrombopoietin Receptor Signaling
TET2 Deficiency Increases the Competitive Advantage of Hematopoietic Stem Cells through Upregulation of Thrombopoietin Receptor Signaling
PRJNA1100587 | ENA
UnknownCompetitiveness analysis of fresh tomatoes in Indonesia: Turning comparative advantage into competitive advantage.
Not available
S-EPMC10688876 | biostudies-literature
TranscriptomicsTET2 Deficiency Increases the Competitive Advantage of Hematopoietic Stem Cells through Upregulation of Thrombopoietin Receptor Signaling
Ten-Eleven Translocation-2 (TET2) mutations drive the expansion of mutant hematopoietic stem cells (HSCs) in clonal hematopoiesis (CH). However, the precise mechanisms by which TET2 mutations confer a competitive advantage to HSCs remain unclear. Here, through an epigenetic drug screen, we discovere...
ORGANISM(S): Mus musculus 
2025-02-11 | GSE264041 | GEO
ProteomicsImpacts of Ser/Thr protein kinase Stk1 on proteome, twitching motility and competitive advantage in Pseudomonas aeruginosaImpacts of Ser/Thr protein kinase Stk1 on proteome, twitching motility and competitive advantage in Pseudomonas aeruginosa
Pseudomonas aeruginosa is a ubiquitous Gram-negative bacterium in the environment and a leading cause of nosocomial infections worldwide. Therefore, it is listed by the World Health Organization as one of the human pathogens that urgently need to develop new antibacterial drugs. Recent findings have...
ORGANISM(S): Pseudomonas aeruginosa PAK 
2021-07-07 | PXD027148 | Pride
Stk1 Ser/thr protein kinase Twitching motility Competitive advantage Pseudomonas aeruginosa. Proteome 
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