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MetabolomicsDifferent regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using in-cell NMR spectroscopy, we d...
2021-10-06 | MTBLS1503 | MetaboLights
UnknownGenetic structure of Tibetan populations in Gansu revealed by forensic STR loci.
Not available
S-EPMC5255561 | biostudies-literature
MetabolomicsPlant species richness promotes the decoupling of leaf and root defence traits while species-specific responses in physical and chemical defences are rare

The increased positive impact of plant diversity on ecosystem functioning over time is often attributed to the gradual accumulation of mutualists and dilution of antagonists in diverse plant communities. While increased plant diversity alters traits related to resource acquisition, it remains unc...

2025-02-13 | MTBLS8464 | MetaboLights
ProteomicsTo explore potential proteins that bind to usp16
HEK293T cells were transfected with FLag-USP16, and cells were performed with co-immunoprecipitation by Flag antibody or IgG with protein A/G beads.
ORGANISM(S): Homo Sapiens 
PXD045021 |
UnknownArtificial intelligence-curated repository of gene-encoded natural diverse components from herbal medicines
Not available
S-EPMC12859667 | biostudies-literature
UnknownPAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas.
Not available
S-EPMC5891348 | biostudies-literature
ProteomicsGlobal identification ofphospho-dependent SCF ubiquitin ligase substrate reveal a role of ERK-FBXO22-BAG3 axis in tumorigenesis
293T cells were cultured in SILAC medium. Heavy group was labeled with K6&R10. Light group was labeled with K0&R0. In light group, cells were treated with MLN4924. In heavy group, cells were treated with DMSO. Then cells were lysed, mixed and tryptic digested. Peptide mixture was subjected to phosph...
ORGANISM(S): Homo Sapiens 
2021-06-29 | PXD027020 |
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