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ProteomicsDeoxyhypusine synthase, an essential enzyme for hypusine biosynthesis, is required for proper exocrine pancreas development
Pancreatic diseases including diabetes and exocrine insufficiency would benefit from therapies that reverse cellular loss and/or restore cellular mass. The identification of molecular pathways that influence cellular growth is therefore critical for future therapeutic generation. Deoxyhypusine synth...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-10-30 | MSV000099697 | MassIVE
ProteomicsA translational regulatory mechanism mediated by hypusinated eukaryotic initiation factor 5A facilitates beta cell identity and function
As professional secretory cells, beta cells require adaptable mRNA translation to facilitate a rapid synthesis of proteins, including insulin, in response to changing metabolic cues. Specialized mRNA translation programs are essential drivers of cellular development and differentiation. However, in ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-10-12 | MSV000093089 | MassIVE
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