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ProteomicsCleavage of RRRRR and RRRRA motifs by rFurin and rKLK8
The project aims to determine where recombinant Furin or KLK8 can cleave a motif found at the cleavage site of Activin-A. A mutation at the fifth arginine was also tested in a R310A peptide to look at the effect of this mutation on the cleavage by these two proteases.
ORGANISM(S): Homo sapiens (Human) 
2025-02-24 | PXD060918 | Pride
Lc-ms/ms 
GenomicsGenome-wide DNA-binding profile of HNF4A and genome occupancy of the histone modifications H3K4me1, H3K27ac in kidneys from Bicc1 WT and KO mice by ChIPseq.
Mutations in Bicaudaul C 1 (BICC1), evolutionary conserved RNA-binding protein, cause renal cysts in mice and humans. These renal cysts are reminiscent of Polycystic Kidney Disease (PKD). How BICC1 is involved in the pathogenesis of polycystic kidney disease is still unknown. Recent studies highligh...
ORGANISM(S): Mus musculus 
2020-01-20 | E-MTAB-6424 | biostudies-arrayexpress
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