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TranscriptomicsRNA-seq of Candida albicans in hyphae inducing conditons treated or not with nicotinamide
In the present study, we investigated whether the acetylation of H3K56, known as relevant for C. albicans virulence, might affect the Candida-macrophages interaction. Therefore, by the mean of the non-specific Hst3 inhibitor nicotinamide (NAM), we evaluated whether the alteration of H3K56 acetylatio...
ORGANISM(S): Candida albicans 
2024-07-29 | E-MTAB-13348 | biostudies-arrayexpress
GenomicsGenome-wide analysis of H3K56ac across C. albicans genome in hyphae-inducing conditions
In the present study, we investigated whether the acetylation of H3K56, known as relevant for C. albicans virulence, might affect the Candida-macrophages interaction. Therefore, by the mean of the non-specific Hst3 inhibitor nicotinamide (NAM), we evaluated whether the alteration of H3K56 acetylatio...
ORGANISM(S): Candida albicans 
2024-07-30 | E-MTAB-13387 | biostudies-arrayexpress
GenomicsH3K56ac profiling in Candida albicans by high throughput sequencing
In C. albicans the sirtuin Hst3p is responsible for removing the acetyl group of the Lys 56 of the H3 histone which is particularly abundant in yeasts and contributes to fungal genome integrity and virulence. Here we identified the H3K56ac patterns across Candida albicans genome in cells maintained ...
ORGANISM(S): Candida albicans 
2022-10-31 | E-MTAB-12193 | biostudies-arrayexpress
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