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GenomicsTNFalpha signaling primes chromatin for NF-kappaB binding and induces rapid and widespread nucleosome repositioning
Background The rearrangement of nucleosomes along the DNA fiber profoundly affects gene expression, but little is known about how signaling reshapes the chromatin landscape, in 3D space and over time, to allow the establishment of new transcriptional programs. Results Using micrococcal nuclease tre...
ORGANISM(S): Homo sapiens 
2014-11-05 | E-GEOD-53343 | biostudies-arrayexpress
TranscriptomicsX chromosome gene expression in D. melanogaster testes
Whole genome expression analyses reveal little evidence for X chromosome dosage compensation or meiotic inactivation in Drosophila testes, whereas testes-specific transgene reporters suggest a novel form of X chromosome-specific regulation. Gene expression was measured in RNA extracted from adult ma...
ORGANISM(S): Drosophila melanogaster 
2011-07-21 | E-GEOD-30850 | biostudies-arrayexpress
TranscriptomicsModeling the clinical phenotype of BTK inhibition in the mature murine immune system
Using the novel BTK inhibitor PF-303, we model the clinical phenotype of BTK inhibition by systematically examining the impact of PF-303 on the mature immune system in mice autoimmune indications. However, our current knowledge of the role of BTK in immune competence has been gathered in the context...
ORGANISM(S): Mus musculus 
2014-08-01 | E-GEOD-56483 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of skeletal muscle tissue from spontaneously hypertensive rats and normotensive rats in a set of recombinant inbred strains
We aimed to identify gene expression profiles/differences between spontaneously hypertensive rat(SHR) and normotensive rat (BN) in a set of recombinant inbred (RI) strains.
ORGANISM(S): Rattus norvegicus 
2008-04-15 | E-TABM-458 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of rat liver from recombinant inbred strains derived from BN and SHR rats
We aimed to identify gene expression profiles/differences between spontaneously hypertensive rat(SHR) and normotensive rat (BN) in a set of recombinant inbred (RI) strains.
ORGANISM(S): Rattus norvegicus 
2011-07-12 | E-MTAB-323 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of rat aorta from recombinant inbred strains derived from BN and SHR rats
We aimed to identify gene expression profiles/differences between spontaneously hypertensive rat(SHR) and normotensive rat (BN) in a set of recombinant inbred (RI) strains.
ORGANISM(S): Rattus norvegicus 
2011-07-12 | E-MTAB-322 | biostudies-arrayexpress
UnknownSARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination.
Not available
S-EPMC9762734 | biostudies-literature
UnknownEfficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Not available
S-EPMC7787219 | biostudies-literature
UnknownElective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.
Not available
S-EPMC7272903 | biostudies-literature
UnknownPreliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa.
Not available
S-EPMC8360544 | biostudies-literature
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