Sort   by:  
 Page size 
TranscriptomicsExpression data in human renal cell carcinoma samples from patients who did or did not respond to anti-PD-1 (Nivolumab) immunotherapy
Pre-treatment tumor expression of PD-L1 has been shown to correlate with favorable clinical outcomes following PD-1 blocking therapies. However, the majority of patients with PD-L1+ tumors do not respond to treatment. With the goal of obtaining insights into the mechanisms underlying the response to...
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-67501 | biostudies-arrayexpress
UnknownFailure to mate enhances investment in behaviors that may promote mating reward and impairs the ability to cope with stressors via a subpopulation of Neuropeptide F receptor neurons.
Not available
S-EPMC10795991 | biostudies-literature
TranscriptomicsHMGA1: A master regulator of tumor progression in triple-negative breast cancer cells
Emerging evidence suggests that tumor cells metastasize by co-opting stem cell transcriptional networks, although the molecular underpinnings of this process are poorly understood. Here, we show for the first time that the high mobility group A1 (HMGA1) gene drives metastatic progression in triple ...
ORGANISM(S): Homo sapiens 
2015-02-18 | E-GEOD-45483 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of primary fibroblasts from a family with autosomal recessive Hutchinson-Gilford Progeria Syndrome
Hutchinson-Gilford progeria syndrome (HGPS) is a genetic disorder displaying features reminiscent of premature senescence caused by germline mutations in the LMNA gene encoding lamin A and C, essential components of the nuclear lamina. By studying a family with homozygous LMNA mutation (K542N), we s...
ORGANISM(S): Homo sapiens 
2011-06-27 | E-MEXP-3097 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human biopsies from normal esophageal epithelium and in vitro cell lines
Comparison of expression profiles of in vitro cell lines with biopsies from human normal esophageal epithelium.
ORGANISM(S): Homo sapiens 
2010-09-01 | E-MEXP-2795 | biostudies-arrayexpress
TranscriptomicsGenome-Wide Methylation Analysis of Breast Cancer Cell Lines
To evaluate the methylation profiles of breast cell lines, we performed methylation profiling of 55 well-characterized breast cancer cell lines on the Illumina HumanMethylation27 (HM27) platform and made use of publicly available methylation profiles of primary breast tumors for comparison. The avai...
ORGANISM(S): Homo sapiens 
2013-03-01 | E-GEOD-42944 | biostudies-arrayexpress
UnknownOptimizing the Use of Gene Expression Profiling in Early-Stage Breast Cancer.
Not available
S-EPMC5455310 | biostudies-literature
TranscriptomicsTranscription profiling of human colon biopsies obtained from patients with ulcerative colitis, Chrohn's disease vs. normal to identify pathogenic processes underlying these disease subtypes
Ulcerative colitis (UC) and Crohn’s disease (CD) are inflammatory bowel diseases (IBD) with variable, overlapping clinical features and complex pathophysiologies. To identify pathogenic processes underlying these disease subtypes, using single endoscopic pinch biopsies to estabolish 36 expression pr...
ORGANISM(S): Homo sapiens 
2007-11-02 | E-GEOD-6731 | biostudies-arrayexpress
GenomicsHomo sapiens
Transcriptional mechanisms of resistance to anti-PD-1 therapy
PRJNA316717 | ENA
GenomicsHomo sapiens
Expression data in human renal cell carcinoma samples from patients who did or did not respond to anti-PD-1 (Nivolumab) immunotherapy
PRJNA280088 | ENA
Sort   by:  
 Page size