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ProteomicsMouse Liver Kupffer Cells LC-MS MS
The importance of immunometabolism in the development of metabolic diseases is clear. Yet, how certain metabolic disorders, such as insulin deficiency (ID), influence immune cell function, and vice versa, is poorly understood. Also, therapeutic strategies to harness the interplay between immune cell...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-15 | PXD062104 | Pride
Mouse Kupffer cells Liver Diabetes 
TranscriptomicsTranscription profiling by array of mice lacking exons 3 to 4 of the Pgc1beta gene (PGC1beta E3,4-/E3,4- mice) against wild type controls to study the role of PGC1beta in metabolism
PGC1beta is a transcriptional coactivator that potently stimulates mitochondrial biogenesis and respiration of cells. Here, we have generated mice lacking exons 3 to 4 of the Pgc1beta gene (PGC1beta E3,4-/E3,4- mice). These mice express a mutant protein that has reduced coactivation activity on a su...
ORGANISM(S): Mus musculus 
2009-04-24 | E-GEOD-6210 | biostudies-arrayexpress
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