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TranscriptomicsA Next-Generation Sequencing Study in a Cohort of Patients with Parkinson’s Disease
Background: Parkinson’s disease (PD) is a multisystem and multifactorial disorder. Therefore, the application of modern genetic techniques may assist in unraveling its complex pathophysiology. Methods: We conducted a clinical-demographic evaluation of 126 patients with PD, all of whom were Caucasian...
ORGANISM(S): Homo sapiens 
2024-10-14 | E-MTAB-13523 | biostudies-arrayexpress
TranscriptomicsLeptin as a Mediator of Tumor-Stromal Interactions Promotes Breast Cancer Stem Cell Activity
Breast cancer stem cells (BCSCs) play crucial roles in tumor initiation, metastasis and resistance to anticancer therapies. These cells rely for their properties on complex interactions with the tumor microenvironment through networks of cytokines and growth factors. In this study, we investigated h...
ORGANISM(S): Homo sapiens 
2015-12-17 | E-MTAB-3641 | biostudies-arrayexpress
TranscriptomicsIdentification of long non-coding RNA expression patterns useful for molecular-based classification of type I endometrial cancers
Endometrial cancer represents the most frequent gynecologic malignant disease. Although several genetic alterations have been associated with increased risk, to date diagnosis and prognosis still rely on morphological features of the tumor, such as histological type, grading and invasiveness. As mol...
ORGANISM(S): Homo sapiens 
2019-04-30 | E-MTAB-7039 | biostudies-arrayexpress
Transcriptomicsendometrial_seq_submission
Endometrial biopsies from tumor (T), adjacent normal (N) and hyperplastic (H) tissue specimens (when available) were obtained by histeroscopy from 10 patients and 3 healty donor. RNA isolated from these samples was used to perform smallRNA-Seq by NGS and gene expression profiling by microarrays in ...
ORGANISM(S): Homo sapiens 
2015-04-01 | E-MTAB-2795 | biostudies-arrayexpress
Transcriptomicsendometrial_array_submission
Endometrial biopsies from tumor (T), adjacent normal (N) and hyperplastic (H) tissue specimens were obtained by histeroscopy from 5 patients
ORGANISM(S): Homo sapiens 
2015-04-01 | E-MTAB-2796 | biostudies-arrayexpress
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