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Mitochondrial function relies on the coordinated transcription of mitochondrial and nuclear genomes to assemble respiratory chain complexes. Across species, the SIN3 coregulator influences mitochondrial functions, but how its loss impacts mitochondrial homeostasis and metabolism in the context of a ...
2024-04-01 | MTBLS8439 | MetaboLights
Transcriptional coregulator NUPR1 maintains tamoxifen resistance in breast cancer cells
Our findings establish a key role for the coregulator, Repressor of Estrogen receptor Activity (REA), in controlling the timing and magnitude of decidualization in human endometrial stromal cells in vitro and in the mouse uterus in vivo, and suggest that REA functions to synchronize uterine differen...
ORGANISM(S): Homo sapiens 
ERG-mediated coregulator complex formation maintains androgen receptor signaling in prostate cancer [ATAC]
ERG-mediated coregulator complex formation maintains androgen receptor signaling in prostate cancer [H3K27ac ChIP]
ERG-mediated coregulator complex formation maintains androgen receptor signaling in prostate cancer [AR ChIP]
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