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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
ProteomicsA novel mechanism for NF-kB activation via IkB aggregation
Proteins which interact with IkBa in insoluble aggregates known as Mallory-Denk bodies were characterized by AP-MS, Biotinylation by antibody recognition (BAR), and LCMS analysis of detergent solubalized aggregates. See the supplementary table (S12) for file annotation.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-08-31 | MSV000086042 | MassIVE
MetabolomicsMulti-omic analysis of vaginal bacteria:host immune and metabolic interactions in early adverse pregnancy outcomes

Objective

To characterise the vaginal microbiota, mucosal metabolome and host immune response in early pregnancy and investigate its relationship with adverse pregnancy outcomes, including ectopic pregnancy, within the context of pregnancies of unknown location (PUL).

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2025-03-28 | MTBLS10098 | MetaboLights
TranscriptomicsMicroarray data from pre-germinated seeds and hypoxia-treated seedlings of Arabidopsis prt6-1 and ate1 ate2 mutants of the N-end rule pathway of targeted proteolysis pathway
This study analyzes transcriptome profiles in pre-germinated seeds and hypoxia-treated seedlings of Arabidopsis thaliana wild type (Col-0) and homozygous mutants (prt6-1 and ate1 ate2). This dataset includes CEL files, RMA signal values and MAS5 P/M/A calls. For pre-germinated seeds, seeds imbibed f...
ORGANISM(S): Arabidopsis thaliana 
2011-10-22 | E-GEOD-29941 | biostudies-arrayexpress
UnknownFactor structure for measures of bystander likelihood, barriers, and actions to prevent problematic alcohol use among college students.
Not available
S-EPMC12078633 | biostudies-literature
UnknownFragmentation pattern of amides by EI and HRESI: study of protonation sites using DFT-3LYP data.
Not available
S-EPMC9080946 | biostudies-literature
UnknownIs the new variant RHDV replacing genogroup 1 in Portuguese wild rabbit populations?
Not available
S-EPMC4306826 | biostudies-literature
UnknownThe crosstalk between Stroke and Cancer: Incidence of cancer after a first-ever cerebrovascular event in a population-based study.
Not available
S-EPMC10472965 | biostudies-literature
ProteomicsCOVID-19 salivary protein profile: unravelling molecular aspects of SARS-COV-2 infection
COVID-19 is the most impacting global pandemic of all times with over 600 million infected and 6.5 million deaths worldwide, in addition to an unprecedented economic impact. Despite the many advances in scientific knowledge about the disease, much remains to be clarified about the molecular alterati...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036571 | Pride
Covid-19  saliva  proteomics  interactomics  oralint 
UnknownCombining hypoxia and bioreactor hydrodynamics boosts induced pluripotent stem cell differentiation towards cardiomyocytes.
Not available
S-EPMC4225049 | biostudies-literature
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