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TranscriptomicsTranscription profiling of human A549 lung cancer cells treated with actinomycin D and sapphyrin PCI-2050 a new class of tumor-selective inhibitors of gene expression.
The goal of this project was to characterize changes in gene expression in response to the anti-cancer agent sapphyrin PCI-2050. Cultured A549 human lung cancer cells were treated with sapphyrin PCI-2050 or actinomycin D.
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-6400 | biostudies-arrayexpress
TranscriptomicsTranscribed ultraconserved region 339 promotes carcinogenesis by sequestering tumor suppressor microRNAs
The transcribed ultraconserved regions (T-UCRs) are a family of long non-coding RNAs implicated in human carcinogenesis. The mechanism of action of T-UCRs and the factors regulating their expression in human cancers are poorly understood. In this study we show that high expression of uc.339 correlat...
ORGANISM(S): Homo sapiens 
2015-07-07 | E-GEOD-70540 | biostudies-arrayexpress
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