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Cortical Dysplasia (CD) is the histopathological substrate in almost half of all drug-resistant epilepsy. Little is known about the gene expression profile of CD. As such information may help target therapeutics more effectively, our aim was to perform a gene expression analysis of an animal model o...
ORGANISM(S): Rattus norvegicus 
Modeling Focal Cortical Dysplasia (FCD) using cortical organoids
Cortical Dysplasia (CD) is the histopathological substrate in almost half of all drug-resistant epilepsy. Little is known about the gene expression profile of CD. As such information may help target therapeutics more effectively, our aim was to perform a gene expression analysis of an animal model o...
ORGANISM(S): Rattus norvegicus 
The cortical area map is initially patterned by transcription factor (TF) gradients in the neocortical primordium, which define a protomap in the embryonic ventricular zone (VZ). However, mechanisms that propagate regional identity from VZ progenitors to cortical plate (CP) neurons are unknown. Here...
ORGANISM(S): Mus musculus 
Dysmorphic neurons express markers of inhibitory glycinergic signaling in focal cortical dysplasia
Cortical Dysplasia (CD) is the histopathological substrate in almost half of all drug-resistant epilepsy. Little is known about the gene expression profile of CD. As such information may help target therapeutics more effectively, our aim was to perform a gene expression analysis of an animal model o...
ORGANISM(S): Rattus norvegicus 
2008-12-10 | GSE13697 | GEO
To clarify the functional properties of FUS, we established the differentially expressed alternative exons in FUS-silenced primary cortical neurons by using exon-sensitive microarray technology. We analyzed total RNA of primary cortical neuron infected with lentivirus expressing shRNA against mouse ...
ORGANISM(S): Mus musculus 
Cortical Dysplasia (CD) is the histopathological substrate in almost half of all drug-resistant epilepsy. Little is known about the gene expression profile of CD. As such information may help target therapeutics more effectively, our aim was to perform a gene expression analysis of an animal model o...
ORGANISM(S): Rattus norvegicus 
2008-12-10 | GSE13676 | GEO
Multimodal single-cell profiling reveals neuronal vulnerability and pathological cell states in focal cortical dysplasia
The specific DNA methylation landscape in Focal Cortical Dysplasia ILAE Type 3D
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