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UnknownInhibition of hypoxia-associated response and kynurenine production in response to hyperbaric oxygen as mechanisms involved in protection against experimental cerebral malaria.
Cerebral malaria (CM) is a multifactorial syndrome involving an exacerbated proinflammatory status, endothelial cell activation, coagulopathy, hypoxia, and accumulation of leukocytes and parasites in the brain microvasculature. Despite significant improvements in malaria control, 15% of mortality is...
S-EPMC6044055 | biostudies-literature
UnknownModeling of <i>Escherichia coli</i> and <i>Listeria monocytogenes</i> Inactivation in Human Milk With a Batch UV-C System: Effect of Agitation, Temperature, and Solids Content.
This study was aimed at evaluating the influence of agitation intensity, initial temperature, and total solids content of milk on the inactivation of Escherichia coli and Listeria monocytogenes by UV-C radiation, with emphasis on a UV-C system in batches for human milk. The kinetic par...
S-EPMC12696034 | biostudies-literature
UnknownOrganic Extract of Justicia pectoralis Jacq. Leaf Inhibits Interferon-γ Secretion and Has Bacteriostatic Activity against Acinetobacter baumannii and Klebsiella pneumoniae.
Justicia pectoralis Jacq. (Acanthaceae) leaves currently found in the Brazilian north-east are widely used to treat diabetes, menstrual pains, asthma, and other disorders. This work aimed to identify the phytochemical characterization and biological activities of J. pectoralis leaf ext...
S-EPMC6126107 | biostudies-literature
UnknownData on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases.
Here, we present the data on the biological effects of Hyptis spp. and Lycium spp. plant extracts in Caenorhabditis elegans (C. elegans) models of neurodegenerative diseases, which is related to the work presented in the article "Neurotherapeutic effect of Hyptis s...
S-EPMC7725741 | biostudies-literature
UnknownDEAD-Box RNA Helicase Family in Physic Nut (Jatropha curcas L.): Structural Characterization and Response to Salinity.
Helicases, motor proteins present in both prokaryotes and eukaryotes, play a direct role in various steps of RNA metabolism. Specifically, SF2 RNA helicases, a subset of the DEAD-box family, are essential players in plant developmental processes and responses to biotic and abiotic stresses. Despite ...
S-EPMC10974417 | biostudies-literature
UnknownFine-scale mapping of a locus for severe bipolar mood disorder on chromosome 18p11.3 in the Costa Rican population.
We have searched for genes predisposing to bipolar disorder (BP) by studying individuals with the most extreme form of the affected phenotype, BP-I, ascertained from the genetically isolated population of the Central Valley of Costa Rica (CVCR). The results of a previous linkage analysis on two exte...
S-EPMC58756 | biostudies-literature
UnknownPrevention of persistent human papillomavirus infection by an HPV16/18 vaccine: a community-based randomized clinical trial in Guanacaste, Costa Rica.
Target groups for human papillomavirus (HPV) vaccination are controversial. We evaluated vaccine efficacy (VE) against 1-year persistent infection, stratified by age and sexual behavior, among young women in Costa Rica. We randomized 7,466 healthy women 18 to 25 years of age to HPV16/18 or hepatitis...
S-EPMC3354733 | biostudies-literature
UnknownAquatic Macrophytes in the Remediation of Atrazine in Water: A Study on Herbicide Tolerance and Degradation Using <i>Eichhornia crassipes</i>, <i>Pistia stratiotes</i>, and <i>Salvinia minima</i>.
Aquatic macrophytes can be used for herbicide remediation provided they exhibit tolerance to the contaminants. This research assessed the remediation potential of Salvinia minima, Echhornia crassipes, and Pistia stratiotes, some common aquatic macrophytes native to Brazil, and t...
S-EPMC11948152 | biostudies-literature
UnknownEquilibrium, Thermodynamic, Reuse, and Selectivity Studies for the Bioadsorption of Lanthanum onto Sericin/Alginate/Poly(vinyl alcohol) Particles.
In a scenario of high demand, low availability, and high economic value, the recovery of rare-earth metals from wastewater is economically and environmentally attractive. Bioadsorption is a promising method as it offers simple design and operation. The aim of this study was to investigate lanthanum ...
S-EPMC7922337 | biostudies-literature
UnknownReduced prevalence of vulvar HPV16/18 infection among women who received the HPV16/18 bivalent vaccine: a nested analysis within the Costa Rica Vaccine Trial.

Background

Vaccine efficacy (VE) against vulvar human papillomavirus (HPV) infection has not been reported and data regarding its epidemiology are sparse.

Methods

Women (n = 5404) age 22-29 present at the 4-year study visit of the Costa Rica Vaccine Trial provided vulvar and cervical ...
S-EPMC4271025 | biostudies-literature
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