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TranscriptomicsRNA-seq analysis reveals significant effects of EGFR signaling on mesenchymal stem cells (MSC)
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goal of this study is to analyse the whole transcriptome of MSCs stimulated with TGFα in order to comprehensively assess the genes regulated by EGFR signalling Methods: Libraries of cDNA wer...
ORGANISM(S): Homo sapiens 
2015-06-26 | E-GEOD-60560 | biostudies-arrayexpress
ProteomicsHistone modifications during acute S-phase defects
Long-term perturbation of de novo chromatin assembly during DNA replication has profound effects on epigenome maintenance and cell fate. The early mechanistic origin of these functional defects is unknown. Here, we combine acute degradation of Chromatin Assembly Factor 1 (CAF-1), a key player in de ...
ORGANISM(S): Homo sapiens (Human) 
2024-11-14 | PXD050618 | Pride
Cell cycle Chromatin assembly Histone chaperones Epigenome stability Dna replication 
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