Sort   by:  
 Page size 
TranscriptomicsIdentification of cranial-specific neural crest genes by comparative transcriptomics
We employ RNA-seq of FACS sorted cell populations to identify genes that are enriched in cranial neural crest in relationship to the trunk. Transcriptional profiling of delaminating cranial and trunk neural crest subpopulations.
ORGANISM(S): Gallus gallus 
2016-06-24 | E-GEOD-75125 | biostudies-arrayexpress
TranscriptomicsADAM13 knockdown in Xenopus laevis cranial neural crest
ADAMs are transmembrane metalloproteases that control cell behavior by cleaving both cell adhesion and signaling molecules. The cytoplasmic domain of ADAMs can regulate the proteolytic activity by controlling the subcellular localization and/or the activation of the protease domain. Here we show tha...
ORGANISM(S): Xenopus laevis 
2011-02-22 | E-GEOD-21517 | biostudies-arrayexpress
TranscriptomicsYap and Taz in Neural Crest play a Crucial Role in Smooth Muscle Development
We conditionally knocked out both Yap and Taz in cranial neural crest (CNC) using the Wnt1Cre driver and sequenced mRNA from embryonic day 10.5 mandibles. Examination of mRNA level in E10.5 mandibular tissues from control and Wnt1Cre Taz and Yap dKO mutant.
ORGANISM(S): Mus musculus 
2016-03-01 | E-GEOD-69311 | biostudies-arrayexpress
GenomicsEnhancer divergence and cis-regulatory evolution in the human and chimpanzee neural crest
Here we derive human and chimpanzee cranial neural crest cells (CNCCs) and profile histone modifications, transcription factors, chromatin accessibility and gene expression to systematically and quantitatively annotate evolutionary divergence of craniofacial cis-regulatory landscapes. Histone modifi...
ORGANISM(S): Homo sapiens 
2015-09-11 | E-GEOD-70751 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse murine dorsal neural tube bisected along the midline with one half from each embryo used for control and the other half treated with 10-6M RA dissolved in ethanol for 6, 12, 24 or 48 h
This series represents murine dorsal neural tube bisected along the midline with one half from each embryo used for control and the other half treated with 10-6M RA dissolved in ethanol for 6, 12, 24 or 48 h. For 6 h exposures, the explants were cultured overnight on fibronectin coated 35mm dishes (...
ORGANISM(S): Mus musculus 
2007-10-11 | E-GEOD-1588 | biostudies-arrayexpress
TranscriptomicsChicken neural crest and neural plate
Neural cest cells are a transient stem cell-like population appearing during vertebrate embryonic development. Generation of the cranial neural crest is known to require a balanced combination of FGF and BMP levels. However, it is poorly understood how the functions of such growth factors are contro...
ORGANISM(S): Gallus gallus 
2012-05-31 | E-GEOD-38381 | biostudies-arrayexpress
TranscriptomicsIdentification of TWIST1 transcriptoinal targets in the cranial mesoderm [WNT1 vs. MESP1]
TWIST1, a basic helix-loop-helix transcription factor is essential for the development of cranial mesoderm and cranial neural crest-derived craniofacial structures. Our previous work showed that, in the absence of TWIST1, some cells within the cranial mesoderm adopt an abnormal epithelial configurat...
ORGANISM(S): Mus musculus 
2016-08-23 | E-GEOD-80335 | biostudies-arrayexpress
TranscriptomicsExpression data from E11.5 mouse branchial arch 1 (BA1) - comparison between Ezh2lox/lox and Wnt1Cre Ezh2lox/lox embryos
Conditional ablation of Ezh2 in the neural crest lineage results in loss of the neural crest-derived mesenchymal derivatives. In this data sheet we determine gene expression analysis in Ezh2lox/lox and Wnt1Cre Ezh2lox/lox in E11.5 mouse BA1 cells. Conditional ablation of Ezh2 in the neural crest lin...
ORGANISM(S): Mus musculus 
2013-11-09 | E-GEOD-52220 | biostudies-arrayexpress
GenomicsSingle-cell multiomic study of zebrafish cranial neural crest [Smart-seq3]
Single-cell multiomic study of zebrafish cranial neural crest [Smart-seq3]
PRJNA1077388 | ENA
GenomicsCHD3 regulates BMP signalling response during cranial neural crest cell specification
CHD3 regulates BMP signalling response during cranial neural crest cell specification
PRJNA1218894 | ENA
Sort   by:  
 Page size