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TranscriptomicsGene expression networks in COPD: microRNA and mRNA regulation
70 miRNAs and 2667 mRNAs were differentially expressed between lung tissue from subjects with COPD and smokers without COPD. miRNA and mRNA expression profiles enriched for biological pathways that may be relevant to the pathogenesis of COPD including the transforming growth factor b, Wnt and focal ...
ORGANISM(S): Homo sapiens 
2012-06-26 | E-GEOD-38974 | biostudies-arrayexpress
TranscriptomicsRegulatory T cell modulation by CBP/EP300 bromodomain inhibition [array]
Genome-wide gene expression changes in response to CBP inhibitor treatment in Treg cells using microarray. Expression profiling by microarray of Treg cells treated with DMSO or CBP inhibitor, and Th0 cells
ORGANISM(S): Homo sapiens 
2016-07-06 | E-GEOD-66596 | biostudies-arrayexpress
GenomicsGenomic Analysis Reveals Distinct Mechanisms and Functional Classes of SOX10-Regulated Genes in Melanocytes [ChIP-Seq]
We performed ChIP-Seq analysis of SOX10, histone H3 lysine 27 acetylation (H3K27ac) and H3K27 trimethylation (H3K27me3) in melanocytes to profile the genomic binding sites of SOX10 and the chromatin landscape. In parallel, we generated Sox10 haploinsufficient cell lines using gene knockout approache...
ORGANISM(S): Mus musculus 
2015-07-03 | E-GEOD-69949 | biostudies-arrayexpress
TranscriptomicsTranscribed ultraconserved region 339 promotes carcinogenesis by sequestering tumor suppressor microRNAs
The transcribed ultraconserved regions (T-UCRs) are a family of long non-coding RNAs implicated in human carcinogenesis. The mechanism of action of T-UCRs and the factors regulating their expression in human cancers are poorly understood. In this study we show that high expression of uc.339 correlat...
ORGANISM(S): Homo sapiens 
2015-07-07 | E-GEOD-70540 | biostudies-arrayexpress
UnknownPerforming Sparse Regularization and Dimension Reduction Simultaneously in Multimodal Data Fusion.
Not available
S-EPMC6618346 | biostudies-literature
UnknownPrediction and Classification of Alzheimer's Disease Based on Combined Features From Apolipoprotein-E Genotype, Cerebrospinal Fluid, MR, and FDG-PET Imaging Biomarkers.
Not available
S-EPMC6805777 | biostudies-literature
UnknownNeurodevelopmental Outcomes of Extremely Preterm Infants Fed Donor Milk or Preterm Infant Formula: A Randomized Clinical Trial.
Not available
S-EPMC10828950 | biostudies-literature
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