Crispri - OmicsDI

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Genomics (938)
Unknown (783)
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Homo sapiens (487)
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synthetic construct (8)
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unidentified plasmid (2)
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Salmonella enterica subsp. enterica (1)
Synechocystis sp. PCC 6803 (1)
Salmonella enterica subsp. enterica serovar Typhimurium (1)
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mixed DNA library (1)
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Piscirickettsia salmonis (1)
Gorilla gorilla (1)
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Organisms

Homo sapiens (473)
Mus musculus (49)
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Escherichia coli str. K-12 substr. MG1655 (4)
Pseudomonas aeruginosa (4)
Saccharomyces cerevisiae (4)
synthetic construct (4)
Vibrio natriegens NBRC 15636 = ATCC 14048 = DSM 759 (2)
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Streptococcus agalactiae CNCTC 10/84 (1)
Mycobacterium tuberculosis variant bovis BCG str. Pasteur 1173P2 (1)
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Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841 (1)
Pseudomonas aeruginosa UCBPP-PA14 (1)
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Repository

ENA (826)
geo (567)
pride (68)
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Disease

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Technology Type

Mass Spectrometry (68)
Shotgun proteomics (36)
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Instrument Platform

6546 Q-TOF LC/MS (Agilent instrument model) (10)
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NA (1)
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Liquid Chromatography MS - (1)
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Liquid Chromatography MS - negative - hilic (1)

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2025 (139)
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2019 (95)
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2022 (46)
2020 (33)
2016 (11)
2018 (10)
2017 (3)

CHEBI ID

CHEBI:18095 (2)
CHEBI:15611 (2)
CHEBI:16283 (2)
CHEBI:16977 (2)
CHEBI:17196 (2)
CHEBI:17115 (2)
CHEBI:16467 (2)
CHEBI:18019 (2)
CHEBI:17203 (2)
CHEBI:18050 (2)
CHEBI:15971 (2)
CHEBI:16857 (2)
CHEBI:17053 (2)
CHEBI:16015 (2)
CHEBI:78682 (2)
CHEBI:15380 (2)
CHEBI:15351 (2)
CHEBI:16108 (2)
CHEBI:14314 (2)
CHEBI:17794 (2)
CHEBI:17621 (2)
CHEBI:15996 (2)
CHEBI:17552 (2)
CHEBI:15422 (2)
CHEBI:32816 (2)
CHEBI:30887 (2)
CHEBI:17489 (2)
CHEBI:16027 (2)
CHEBI:25523 (2)
CHEBI:16474 (2)

Metabolite Name

D-Fructose 1,6-bisphosphate (2)
Succinyl coenzyme A (2)
Cyclic AMP (2)
Adenosine monophosphate (2)
NADP (2)
NADPH (2)
L-Malic acid (2)
D-Glucose 6-phosphate (2)
Sarcosine (2)
NADH (2)
Pyruvate (2)
Acetyl-CoA_HMDB0001206 (1)
FAD_HMDB0001248 (1)
Coenzyme A_HMDB0001423 (1)
NADP_HMDB0000217 (1)
Stachyose_HMDB0003553 (1)
NADH_HMDB0001487 (1)
NAD_HMDB0000902 (1)
Uridine diphosphate-N-acetylglucosamine_HMDB0000290 (1)
Guanosine diphosphate mannose_HMDB0001163 (1)
Uridine diphosphate glucose_HMDB0000286 (1)
Taurocholic acid_HMDB0000036 (1)
Adenosine triphosphate_HMDB0000538 (1)
Raffinose_HMDB0003213 (1)
Taurodeoxycholic acid_HMDB0000896 (1)
Deoxycholic acid glycine conjugate_HMDB0000631 (1)
Adenosine diphosphate_HMDB0001341 (1)
Sucrose 6-Phosphate_No HMDB data (1)
Cholic acid_HMDB0000619 (1)
3-Oxocholic acid_HMDB0000502 (1)

First Public Date

2025 (201)
2024 (152)
2026 (126)
2023 (94)
2022 (68)
2021 (64)
2020 (57)
2019 (33)
2018 (18)
2017 (7)
2016 (6)

Classification

bacteria (46)

Study type

RNA-seq of coding RNA (7)
DNA-seq (5)
RNA-seq of coding RNA from single cells (2)
Cell line - High-throughput sequencing (1)
Other (1)
ChIP-seq (1)
Transcription profiling by array (1)
RNA-seq of total RNA (1)
RNA-seq of non coding RNA (1)

Release Date

2025 (160)
2024 (137)
2023 (120)
2022 (108)
2021 (87)
2020 (56)
2019 (41)
2018 (31)
2026 (20)
2016 (19)
2017 (18)
2015 (3)
2014 (3)

Lab affiliation

Department of Microbiology and Immunology, The University of Melbourne, Victoria, Australia (19)
Staff Scientist Biological Systems & Engineering Division Lawrence Berkeley National Laboratory Berkeley CA 94720 (9)
Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, 792 Elizabeth Street, Melbourne, VIC 3000, Australia. (3)
Department of Molecular and Cellular Biology, College of Biological Sciences, University of California, Davis, CA, 95616, USA (3)
Department of Microbiology and Immunology, University of Melbourne, Victoria, Australia (2)
1 Hudson Institute of Medical Research, Clayton, VIC, Australia, 2 Department of Molecular and Translational Sciences, Monash University, Clayton, VIC, Australia (1)
Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia (1)
Calico Life Sciences (1)
Carnegie MS Facility (1)
Charles Perkins Centre, School of Medical Sciences, University of Sydney, Sydney, Australia. (1)
City University of Hong Kong (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA (1)
Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Switzerland (1)
Department of Chemistry and Sarafan ChEM-H (1)
Department of Laboratory Medicine, UCSF (1)
Department of Medical Biology, UiT- The Arctic University of Norway, 9019 Tromsø, Norway (1)
Department of Microbial Proteomics, Institute of Microbiology, Center for Functional Genomics of Microbes, University of Greifswald, Felix-Hausdorff-Str. 8, 17489 Greifswald, Germany (1)
Dept of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, Sweden (1)
Head of MRC LMS proteomics core (1)
Head, Translational Antigen Discovery Lab Department of Medicine/ School of Clinical Sciences at Monash Health Monash University Level 7, TRF Building, Monash Medical Centre 246 Clayton Road Clayton VIC 3168 Australia M: +61 415126562 (1)
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA Department of Medicine and Division of Hematology/Oncology, University of California, San Francisco, San Francisco, CA 94158, USA (1)
Koch Institute for Integrative Cancer Research at MIT (1)
Lab of Proteome Research, Department of Molecular Biology and Genetics, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia (1)
Laboratory of Molecular Environmental Microbiology, Department of Environmental Science and Ecological Engineering, Korea University, Seoul 02841, Republic of Korea (1)
Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Department of Biochemistry and Biophysics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. (1)
MIT (1)
MPI of Biochemistry, Am Klopferspitz 18, 82152 Planegg, Germany (1)
Max Planck Institute for terrestrial Microbiology Karl von Frisch Str. 10 35043 Marburg Germany (1)
Max Planck Unit for the Science of Pathogens, D-10117 Berlin, Germany Institute of Microbiology, Leibniz Universität Hannover, Hannover, Germany (1)
Molecular Genetics RPTU Kaiserslautern (1)

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Whole genome CRISPRi screening identifies druggable vulnerabilities in drug-resistant Mycobacterium tuberculosis

Tuberculosis (TB) remains a global health threat, aggravated by the emergence of drug-resistant strains. This study aims to identify genes and metabolic pathways with increased vulnerability in drug-resistant Mycobacterium tuberculosis strains compared to their drug-susceptible counterparts. Usin...

2024-10-15 | MTBLS11277 | MetaboLights

14028s CRISPRi Bile salts

Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S CRISPRi library, growth with and without bile salts.

ORGANISM(S): Salmonella enterica subsp. enterica

2026-04-15 | E-MTAB-16844 | biostudies-arrayexpress

Next-Generation Sequencing of sgRNA spacer sequences from a CRISPRi library screen of the Salmonella enterica serovar Typhimurium 14028s genome in response to repeated monoclonal IgA treatment

For this study, we implemented the anti-lipopolysaccharide monoclonal IgA Sal4 in a genome-wide CRISPR interference (CRISPRi) screen to identify genes that modulate the extent of agglutination of Salmonella enterica serovar Typhimurium (STm) in response to antibody exposure. We leveraged our recentl...

ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium

2025-02-16 | E-MTAB-14834 | biostudies-arrayexpress

14028s CRISPRi Bile salts

PRJEB111027 | ENA

Jurkat CRISPRi ATAC-seq [Series 3]

PRJNA1088439 | ENA

RNA-seq of CSMD1 enhancer CRISPRi in LUHMES cells and differentiated neurons

we performed lentiviral CRISPR interference (CRISPRi) by recruiting dCas9 fused with the KRAB domain to the CSMD1 enhancer (fam3) in the neuronal precursor cell line – Lund human mesencephalic (LUHMES). Given that the expression of CSMD1 was not detectable in LUHMES cells we differentiated these cel...

ORGANISM(S): Homo sapiens

2022-06-30 | E-MTAB-8027 | biostudies-arrayexpress

CRISPRi DSP-kd in iAT2

PRJNA781443 | ENA

CRISPRi knockdowns

Multi-omics analysis of CRISPRi-knockdowns identifies mechanisms that buffer decreases of enzymes in E. coli metabolism

PRJEB40851 | ENA

CRISPRi/a screen of doxorubicin induced cardiotoxicity

PRJNA1155211 | ENA

Genome-scale CRISPRi screen identifies pcnB repression conferring overproduction of free fatty acids in Escherichia coli

In this study, we carried out genome-scale CRISPRi modulation combining fluorescence-activated cell sorting (FACS) and next-generation sequencing (NGS) to identify genetic determinants for FFAs overproduction in Escherichia coli. The pcnBi (AP) strain that repressed the expression of pcnB produced 2...

ORGANISM(S): Escherichia Coli

2024-05-18 | PXD052390 |

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2291 Results

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