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TranscriptomicsCrkII transgene induces atypical mammary gland development and tumorigenesis
The v-Crk protein was originally isolated as the oncogene fusion product of the CT10 chicken retrovirus. Cellular homologues of v-Crk include Crk, which encodes two alternatively spliced proteins (CrkI and CrkII), and CrkL. Though CrkI/II proteins are elevated in several types of cancer, including b...
ORGANISM(S): Homo sapiens 
2011-07-17 | E-GEOD-30731 | biostudies-arrayexpress
TranscriptomicsTransgenic overexpression of CRK in neonatal skeletal muscle
Transcriptome analysis of M. quadriceps of Mus musculus after HSA (human α-skeletal actin promoter)-driven transgenic overexpression of CRK.
ORGANISM(S): Mus musculus 
2022-03-22 | E-MTAB-10228 | biostudies-arrayexpress
GenomicsCRK proteins are essential for SRC/FAK signaling in EMT
Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial-mesenchymal transition and colorectal cancer aggressiveness
PRJEB36353 | ENA
UnknownDok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L.
Not available
S-EPMC2964755 | biostudies-literature
GenomicsMus musculus
Crk/CrkL morphological analysis project
PRJDB9602 | ENA
ProteomicsCRK binding partners and proteomics of control and miR-1/206/133 tKO quadriceps
Immunoprecipitation of CRK protein followed by mass spectrometry identification of binding partners and mass spectrometry proteomics of control and miR-1/206/133 tKO quadriceps
ORGANISM(S): Mus Musculus (mouse) 
2022-04-01 | PXD032882 | JPOST Repository
TranscriptomicsCrk mediates Csk-Hippo signaling independently of Yap tyrosine phosphorylation to induce cell competition
Src family kinases (SFKs), including Src, Fyn and Yes, play important roles in development and cancer. Despite being first discovered as the Yes-associated protein, the regulation of Yap by SFKs remains poorly understood. Here, through single-cell analysis and genetic lineage tracing, we show that t...
ORGANISM(S): Mus musculus 
2025-01-19 | GSE253784 | GEO
GenomicsCrk mediates Csk-Hippo signaling independently of Yap tyrosine phosphorylation to induce cell competition
Crk mediates Csk-Hippo signaling independently of Yap tyrosine phosphorylation to induce cell competition
PRJNA1067127 | ENA
UnknownStructure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide.
Not available
S-EPMC137835 | biostudies-literature
UnknownCrk and CrkL adaptor proteins: networks for physiological and pathological signaling.
Not available
S-EPMC2689226 | biostudies-literature
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