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TranscriptomicsMeasuring the effects of hypoxia on transcription in Caulobacter crescentus
To test the effects of hypoxia on transcription in Caulobacter crescentus, we cultured cells in a New Brunswick bioreactor under controlled conditions. Prior to innoculation, the medium was bubbled with laboratory air at maximum flow and stirred at 300 rpm for 2 hours. After this period, the mediu...
ORGANISM(S): Caulobacter vibrioides 
2010-06-21 | E-GEOD-21127 | biostudies-arrayexpress
TranscriptomicsMeasuring transcriptional differences between Caulobacter crescentus cultured in nitrate versus ammonium as the sole nitrogen source
This study is measuring the steady-state levels of mRNA in wild-type Caulobacter crescentus grown in M2 defined medium containing either ammonium or nitrate as the sole nitrogen source. Four independent cultures of Caulobacter crecentus were grown in each of two medium conditions: M2(nitrate)glucose...
ORGANISM(S): Caulobacter vibrioides 
2010-06-20 | E-GEOD-21203 | biostudies-arrayexpress
TranscriptomicsTesting the effects of nitric oxide (oxidative) stress on Caulobacter transcription
The goal of this study was to measure the effects of nitric oxide exposure (using DETA NONOate as a nitric oxide donor) on transcription in Caulobacter. Untreated Caulobacter crescentus were grown to a density of 0.3 (at OD660) in PYE medium (pH 7) in rolled culture tubes. DETA-NONOate treated Cau...
ORGANISM(S): Caulobacter vibrioides 
2010-06-20 | E-GEOD-21139 | biostudies-arrayexpress
TranscriptomicsTesting the effect of coordinate overexpression of the lovK-lovR two component system on the Caulobacter transcriptome
This experiment is testing the effects of coordinate overexpression of the lovK-lovR two-component system on gene expression in Caulobacter crescentus relative to an empty vector control strain. Transcription in two independent cultures of a lovK-lovR overexpression strain (FC438) are compared to tw...
ORGANISM(S): Caulobacter vibrioides 
2012-05-31 | E-GEOD-21204 | biostudies-arrayexpress
TranscriptomicsComparing the transcriptional profiles of a Caulobacter crescentus phyR null mutant to a xylose-inducible phyR overexpression strain
phyR encodes a general stress regulator protein that is conserved among several alpha-proteobacteria. This experiment is quantifying transcription in two Caulobacter strains: one strain is overexpressing phyR (gene CC3477); the other carries a phyR in-frame deletion. Both strains were cultured in ...
ORGANISM(S): Caulobacter vibrioides 
2012-05-31 | E-GEOD-21205 | biostudies-arrayexpress
TranscriptomicsComparing the transcriptional profiles of a Caulobacter crescentus CB15N (NA1000) wild-type to a SpoT null in carbon starvation.
SpoT is an Rsh (Rel / Spo homolog) protein, which synthesizes the alarmone ppGpp in response to starvation. This experiment is quantifying transcription in two Caulobacter strains after 5 minutes of glucose starvation: one strain is wild-type CB15N (NA1000); the other strain is NA1000 which has a c...
ORGANISM(S): Caulobacter vibrioides 
2011-05-01 | E-GEOD-21206 | biostudies-arrayexpress
UnknownRegional brain metabolism differs between narcolepsy type 1 and idiopathic hypersomnia.
Not available
S-EPMC8361346 | biostudies-literature
UnknownCrystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii.
Not available
S-EPMC1302813 | biostudies-literature
UnknownStructural basis of a protein partner switch that regulates the general stress response of α-proteobacteria.
Not available
S-EPMC3361416 | biostudies-literature
MetabolomicsNon-redundant cardiolipin synthase family proteins shape lipid composition and stress resilience in Bacteroides fragilis

Gut-resident bacteria must withstand membrane-disrupting stresses such as bile acids to persist in the intestinal environment. The Bacteroidota are a dominant phylum of the human gut microbiota. However, the genes responsible for synthesis of membrane lipids in this phylum remain relatively uncha...

2026-10-06 | MTBLS11891 | MetaboLights
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