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TranscriptomicsGlucocorticoids in maintaining cardiac homeostasis in C57bl/6 (wild-type) mice
To further understand the genomic effects of glucocorticoids in the heart we performed microarray studies on hearts collected from long-term ADX-mice. Our objective is to find cardiac specific genes regulated by glucocorticoids. C57bl/6 (wild-type) mice were adrenalectomized. Hearts were collected f...
ORGANISM(S): Mus musculus 
2016-06-09 | E-GEOD-83202 | biostudies-arrayexpress
MetabolomicsFunctional Characterization of the Lin28/let-7 Circuit During Forelimb Regeneration in Ambystoma mexicanum and Its Influence on Metabolic Reprogramming
The axolotl (Ambystoma mexicanum) is a caudate amphibian, which has an extraordinary ability to restore a wide variety of damaged structures by a process denominated epimorphosis. While the origin and potentiality of progenitor cells that take part during epimorphic regeneration are known to ...
2021-11-04 | MTBLS1708 | MetaboLights
TranscriptomicsRNA-sequencing of human umbilical cord-derived MSC (UCX) in normoxia and hypoxia
Human umbilical cord matrix-derived mesenchymal stromal cells (UCM-MSC) are advantageous since can be easily obtained and display special interest as universal and feasible add-on therapy for myocardial infarction (MI). In this study, UCM-MSC from two umbilical cords, UC-A and UC-B, were transplante...
ORGANISM(S): Homo sapiens 
2021-01-07 | E-MTAB-9978 | biostudies-arrayexpress
GenomicsWhole genome sequencing of tumour and normal paired samples of diffuse intrinsic pontine gliomas
Diffuse intrinsic pontine glioma (DIPG) have a universally dismal prognosis (median 9-12 months), with neither chemotherapeutic nor targeted agents showing any substantial survival benefit in clinical trials in children with these tumours. DIPG are highly infiltrative malignant glial neoplasms of th...
EGAS00001000572 | EGA
Genomicsena-DATASET-INSTITUTE OF CANCER RESEARCH-17-12-2013-15:22:20:271-113 - samples
Whole exome sequencing of 6 tumour and normal pairs of diffuse intrinsic pontine glioma (DIPG)
EGAD00001000706 | EGA
Genomicsena-DATASET-INSTITUTE OF CANCER RESEARCH-17-12-2013-15:02:33:112-168 - samples
Whole genome sequencing of 20 tumour and normal pairs of diffuse intrinsic pontine glioma (DIPG)
EGAD00001000705 | EGA
GenomicsICR DIPG Data Access Committee
Data Access Committee EGAC00001000148
EGAC00001000148 | EGA
GenomicsNkx2-1 Represses a Latent Gastric Differentiation Program in Lung Adenocarcinoma
Tissue-specific differentiation programs become dysregulated during cancer evolution. The transcription factor Nkx2-1 is a master regulator of pulmonary differentiation that is downregulated in poorly differentiated lung adenocarcinoma. Here we use conditional murine genetics to study the fate of l...
ORGANISM(S): Mus musculus 
2013-04-09 | E-GEOD-43252 | biostudies-arrayexpress
UnknownLTA4H rs2660845 association with montelukast response in early and late-onset asthma.
Not available
S-EPMC8457475 | biostudies-literature
UnknownNovel SNP array analysis and exome sequencing detect a homozygous exon 7 deletion of MEGF10 causing early onset myopathy, areflexia, respiratory distress and dysphagia (EMARDD).
Not available
S-EPMC3940074 | biostudies-literature
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