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ProteomicsElevated NAD+ drives Sir2A-mediated GCβ deacetylation and localization for Plasmodium ookinete gliding and mosquito infection
cGMP signal-activated ookinete gliding is essential for mosquito midgut infection of Plasmodium in malaria transmission. During ookinete development, cGMP synthesizer GCβ polarizes to a unique localization “ookinete extrados site” (OES) until ookinete maturation and activates cGMP signaling for init...
ORGANISM(S): Plasmodium Yoelii Yoelii 17xnl 
2024-09-26 | PXD056305 |
ProteomicsProteomic analysis of dwarf mutant of Medicago truncatula
Wild type and a dwarf mutant of Medicago truncatula genotype R108 were analyzed by iTRAQ
ORGANISM(S): Medicago Truncatula 
2021-05-31 | PXD026363 |
ProteomicsApical anchorage and stabilization of subpellicular microtubules by apical polar ring ensures Plasmodium ookinete infection in mosquito
Morphogenesis of many protozoans depends on a polarized establishment of cortical cytoskeleton possessing the subpellicular microtubules (SPMTs), which are apically nucleated and anchored by the apical polar ring (APR). In the malaria parasite Plasmodium, APR can be observed when a round zygote diff...
ORGANISM(S): Plasmodium Yoelii Yoelii 17xnl 
2022-11-18 | PXD038209 |
ProteomicsInner membrane complex proteomics reveals a palmitoylation cascade regulating intraerythrocytic development of malaria parasite
Malaria is caused by infection of the erythrocytes by the parasites Plasmodium. Inside the erythrocytes, the parasites grow and multiply via schizogony, an unconventional cell division mode. The Inner Membrane Complex (IMC), an organelle located beneath the plasma membrane of the parasites, is essen...
ORGANISM(S): Plasmodium Yoelii Yoelii 17xnl 
2022-07-01 | PXD028193 |
ProteomicsAn axonemal intron splicing program sustains Plasmodium male development
To gain further insights into the post-transcriptional regulation process in the male sexual stage of Plasmodium, we focused on RBPm1, the most specifically expressed RNA-binding protein in the male gametocyte of P. yoelii, for in-depth investigation. In the first part of this study, we identified R...
ORGANISM(S): Plasmodium Yoelii Yoelii 17xnl 
2023-07-26 | PXD044094 |
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