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GenomicsH3K27me3 ChIP-seq experiment in fruitfly testis somatic gonadal cells
In many metazoans, germ cells are separated from somatic lineages early in development and maintain their identity throughout life. Here we show that a Polycomb group (PcG) component, Enhancer of Zeste [E(z)] H3K27me3-specific methyltransferase, maintains germline identity in Drosophila adult testes...
ORGANISM(S): Drosophila melanogaster 
2014-05-02 | E-GEOD-53238 | biostudies-arrayexpress
UnknownBifunctional iron-catalyzed alkyne Z-selective hydroalkylation and tandem Z-E inversion via radical molding and flipping.
Not available
S-EPMC11452693 | biostudies-literature
UnknownResearch on multi-objective optimization method of Z-shaped pipeline structure based on Kriging model.
Not available
S-EPMC11604928 | biostudies-literature
GenomicsMapping Epigenomic Type-Specific Differences Occurring During Hematopoiesis [ChIP-Seq]
Formation of the blood from self-renewing hematopoietic stem cells to terminal lineages necessarily involves epigenomic modifications of the genome to control regulator and signature gene expression. By analysing the global expression profiles of hematopoietic stem cells (HSCs), in vivo differentiat...
ORGANISM(S): Homo sapiens 
2013-03-25 | E-GEOD-39538 | biostudies-arrayexpress
Unknown(Z)-(1,2-Dichloro-vin-yl)diphenyl-phosphine oxide.
Not available
S-EPMC3200614 | biostudies-literature
TranscriptomicsMapping Epigenomic Type-Specific Differences Occurring During Hematopoiesis
Formation of the blood from self-renewing hematopoietic stem cells to terminal lineages necessarily involves epigenomic modifications of the genome to control regulator and signature gene expression. By analysing the global expression profiles of hematopoietic stem cells (HSCs), in vivo differentiat...
ORGANISM(S): Homo sapiens 
2013-03-25 | E-GEOD-39229 | biostudies-arrayexpress
UnknownA non-cell autonomous role of E(z) to prevent germ cells from turning on a somatic cell marker.
Not available
S-EPMC4040133 | biostudies-literature
GenomicsChromatin Signatures in Multipotent Human HSCs Indicate the Fate of Bivalent Genes during Differentiation
Histone modifications have been implicated in stem cell maintenance and differentiation. We have analyzed genome-wide changes in gene expression and histone modifications during differentiation of multipotent human primary hematopoietic stem cells/progenitor cells (HSCs/HPCs) into erythrocyte precur...
ORGANISM(S): Homo sapiens 
2009-01-09 | E-GEOD-12646 | biostudies-arrayexpress
UnknownMutations in NEXN, a Z-disc gene, are associated with hypertrophic cardiomyopathy.
Not available
S-EPMC2978958 | biostudies-literature
UnknownPolycomb Group Gene E(z) Is Required for Spermatogonial Dedifferentiation in Drosophila Adult Testis.
Not available
S-EPMC5516936 | biostudies-literature
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