Sort   by:  
 Page size 
TranscriptomicsThe viral and cellular microRNA targetome in lymphoblastoid cell lines
Epstein-Barr virus (EBV) is a human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role...
ORGANISM(S): Homo sapiens 
2012-10-16 | E-GEOD-41437 | biostudies-arrayexpress
TranscriptomicsDifferential RISC association of endogenous human microRNAs predicts their inhibitory potential
It has previously been assumed that the generally high stability of microRNAs (miRNAs) reflects their tight association with Argonaute (Ago) proteins, essential components of the RNA-induced silencing complex (RISC). However, recent data have suggested that the majority of mature miRNAs are not, in ...
ORGANISM(S): Homo sapiens 
2014-05-30 | E-GEOD-58127 | biostudies-arrayexpress
TranscriptomicsBJAB Cell Lines Unmodified, Transduced with ith lentiviral vector pNL-SIN-CMV-AcGFP or pNL-SIN-CMV-AcGFP/miR-K12-11
All metazoan eukaryotes express microRNAs (miRNAs), ~22 nt long regulatory RNAs that can repress the expression of mRNAs bearing complementary sequences. Several DNA viruses also express miRNAs in infected cells, suggesting a role in viral replication and pathogenesis. While specific viral miRNAs ha...
ORGANISM(S): Homo sapiens 
2007-12-18 | E-GEOD-8867 | biostudies-arrayexpress
TranscriptomicsIdentification of novel, highly expressed retroviral microRNAs in cells infected by bovine foamy virus
While numerous viral microRNAs (miRNAs) expressed by DNA viruses, especially herpesvirus family members, have been reported, there have been very few reports of miRNAs derived from RNA viruses. Here we describe three miRNAs expressed by bovine foamy virus (BFV), a member of the spumavirus subfamily ...
ORGANISM(S): Bos taurus 
2015-04-07 | E-GEOD-67620 | biostudies-arrayexpress
TranscriptomicsDepletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding [expression array data]
The t(8;21) translocation fuses the DNA binding domain of the hematopoietic master regulator RUNX1 to the ETO protein. The resultant RUNX1/ETO fusion protein is a leukemia-initiating transcription factor that interferes with RUNX1 function. The result of this interference is a block in differentiati...
ORGANISM(S): Homo sapiens 
2012-03-27 | E-GEOD-29223 | biostudies-arrayexpress
TranscriptomicsDepletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding (Illumina expression)
The t(8;21) translocation fuses the DNA binding domain of the hematopoietic master regulator RUNX1 to the ETO protein. The resultant RUNX1/ETO fusion protein is a leukemia-initiating transcription factor that interferes with RUNX1 function. The result of this interference is a block in differentiati...
ORGANISM(S): Homo sapiens 
2012-03-27 | E-GEOD-34594 | biostudies-arrayexpress
GenomicsDepletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding
The t(8;21) translocation fuses the DNA binding domain of the hematopoietic master regulator RUNX1 to the ETO protein. The resultant RUNX1/ETO fusion protein is a leukemia-initiating transcription factor that interferes with RUNX1 function. The result of this interference is a block in differentiati...
ORGANISM(S): Homo sapiens 
2012-03-26 | E-GEOD-29225 | biostudies-arrayexpress
TranscriptomicsPrimary effusion lymphoma cell lines BC-1 and BC-3
Microarray analysis of primary effusion lymphoma cell lines BC-1 and BC-3 Total RNA from BC-1 and BC-3 cell lines was processed for analysis in one replicate on Human Gene 1.0 ST arrays to obtain data on whether genes are expressed and to compare to existing microarray data.
ORGANISM(S): Homo sapiens 
2011-11-16 | E-GEOD-31745 | biostudies-arrayexpress
TranscriptomicsBJAB Cell Lines Transduced with lentiviral vector pNL-SIN-CMV-AcGFP expressing KSHV miRNAs miR-K1, miR-K12-11, or miR-K4-3p
BJAB cells were infected with pNL-SIN-CMV-AcGFP (see accession number GSE8867 for data) or pNL-SIN-CMV-AcGFP expressing KSHV miR-K1, miR-K12-11 or miR-K4-3p and sorted 48 hours after infection. 12 or 16 days after transduction, cytoplasmic RNA was harvested and gene expression analysis of independen...
ORGANISM(S): Homo sapiens 
2011-11-16 | E-GEOD-31746 | biostudies-arrayexpress
Sort   by:  
 Page size