Sort   by:  
 Page size 
TranscriptomicsLineage relationship in human dendritic cells
The lineage relationships and fate of human blood and tissue dendritic cells (DC) has significance for a number of diseases including HIV where both blood and tissue DC may be infected. We used gene expression profiling of monocyte and DC sub-populations sorted directly from blood and skin and compa...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-32400 | biostudies-arrayexpress
TranscriptomicsLineage relationship in human dendritic cells - cDNA arrays
The lineage relationships and fate of human blood and tissue dendritic cells (DC) has significance for a number of diseases including HIV where both blood and tissue DC may be infected. We used gene expression profiling of monocyte and DC sub-populations sorted directly from blood and skin and compa...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-32648 | biostudies-arrayexpress
TranscriptomicsTowards an understanding of the mechanism of action of praziquantel
Although praziquantel (PZQ) has been used to treat schistosomiasis for over 20 years its mechanism of action remains unknown. We have developed an assay based on the transcriptional response of S. mansoni PR-1 to heat shock to confirm that while 6 week post infection (p.i.) schistosomes are sensitiv...
ORGANISM(S): Schistosoma mansoni 
2008-11-10 | E-GEOD-12850 | biostudies-arrayexpress
TranscriptomicsMicroarray based analysis of temperature and oxidative stress induced messenger RNA in Schistosoma mansoni
The body’s defense against schistosome infection can take many forms. For example, upon developing acute schistosomiasis, patients often have fever coinciding with larval maturation, migration and early oviposition. As the infection becomes established, the parasite comes under oxidative stress gene...
ORGANISM(S): Schistosoma mansoni 
2008-08-25 | E-GEOD-11706 | biostudies-arrayexpress
MetabolomicsDysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multi-drug resistance exceeding 80% and 40%, respectively. The innate immune response generates a variety of antimicrobial agents to control infection including zinc stres...

2022-02-23 | MTBLS318 | MetaboLights
TranscriptomicsTranscription profiling of rat kidney exposed to different doses of Cisplatin- ILSI-HESI NephroToxicity Study - Cisplatin
Evaluation and comparison of biological responses of rats and gene expression responses of the kidney in rats exposed to different doses of Cisplatin [CAS:15663-27-1;CHEBI:27899]
ORGANISM(S): Rattus norvegicus 
2007-01-10 | E-TOXM-11 | biostudies-arrayexpress
TranscriptomicsCalvarial osteoblast transcriptome analysis identifies genetic targets and extracellular matrix-mediated focal adhesion as potential biomarkers for single-suture craniosynostosis
Craniosynostosis is a disease defined by premature fusion of one or more cranial sutures. The mechanistic pathology of isolated single-suture craniosynostosis is complex and while a number of genetic biomarkers and environmental predispositions have been identified, in many cases the causes remain c...
ORGANISM(S): Homo sapiens 
2012-03-04 | E-GEOD-27976 | biostudies-arrayexpress
TranscriptomicsIn vivo polarization of Ovalbumin (OVA)-specific CD4 (OTII) T cells
There remains a need for analysis of CD4 helper T cells differentiation in vivo. To this end ovalbumin (OVA)-specific CD4 (OTII) T cells transferred into congenic mice were studied. Live attenuated OVA-expressing Salmonella (SalOVA) induce T-bet and IFN-g in OTII cells, while alum-precipitated OVA (...
ORGANISM(S): Mus musculus 
2008-06-27 | E-GEOD-7481 | biostudies-arrayexpress
MetabolomicsInhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells

BACKGROUND: Neuroblastoma accounts for 7% of paediatric malignancies but is responsible for 15% of all childhood cancer deaths. Despite rigorous treatment involving chemotherapy, surgery, radiotherapy and immunotherapy, the 5-year overall survival rate of high-risk disease remai...

2022-11-30 | MTBLS858 | MetaboLights
UnknownMovement Demands of Elite Under-20s and Senior International Rugby Union Players.
Not available
S-EPMC5100986 | biostudies-literature
Sort   by:  
 Page size