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ProteomicsThe Deuterium Calculator HDX-MS Data Analysis
Hydrogen-deuterium exchange mass spectrometry (HDX-MS) is a powerful protein footprinting technique to study protein dynamics and binding; however, HDX-MS data analysis is often challenging and time consuming. Moreover, the HDX community is expanding to investigate multi-protein and highly complex p...
ORGANISM(S): Escherichia coli 
2023-01-30 | PXD036813 | Pride
Hydrogen-deuterium exchange mass spectrometry Subzero temperature uplc Hdx data analysis software Hdx-ms 
ProteomicsQuantitative Top-Down Proteomics Analysis of Age-related Changes in Murine Hearts
Label-free quantitative top-down proteomics was performed on mitochondrial lysate isolated from the hearts of 3 young (4-month-old) and 3 old (24-25-month-old) mice.
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD051505 | Pride
Top-down Quantitative Aging 
ProteomicsIntact Protein TMT Labeling and 2D High-pH/Low-pH RP/RPLC-MS/MS
Optimization of intact protein TMT labeling and multidimensional high-pH/low-pH RP/RPLC-MS/MS. Application of this platform for quantification of proteoform-level abundance changes as a result of staursporine treatment in HeLa cells.
ORGANISM(S): Homo sapiens (Human) 
2026-08-13 | PXD078120 | Pride
Tmt labeling Top-down proteomics Multidimensional lc-ms 
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