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PKR is an interferon induced serine/threonine protein kinase, that is activated by double stranded RNA. PKR plays an important role in the antiviral defense by interferon. In addition to its role in translation, PKR participates in several signaling pathways to transcription. The goal of this experi...
ORGANISM(S): Mus musculus 
This is a model of neuronal Nitric Oxide Synthase expressed in Escherichia coli based on Santolini J. et al. J Biol Chem. (2001) 276(2):1233-43. Differing from the article, oxygen explicitly included in the reaction 2, 5 and 10 (numbers as in scheme 1 in th...
2024-09-02 | BIOMD0000000199 | BioModels
Dynamic genome folding plays a crucial role in cellular functions, including V(D)J recombination at the immunoglobulin kappa (Igκ) locus for antibody generation. This process involves frequent recombination between Jκ and Vκ gene segments over a 3.2 Mb region in both deletional and inversional orien...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-20 | PXD058006 | Pride
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