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TranscriptomicsHigh-throughput sequencing reveals key genes and immune homeostatic pathways activated in myeloid dendritic cells by Porphyromonas gingivalis 381 and its fimbrial mutants
Periodontitis affects 47.1% of adult population in the U.S. Porphyromonas gingivalis is an opportunistic oral pathogen that colonizes the oral mucosa, invades myeloid dendritic cells and accesses the bloodstream, brain, placenta and other organs in human with periodontitis. Periodontitis also sustai...
ORGANISM(S): Homo sapiens 
2016-07-21 | E-GEOD-67141 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of major osmoregulatory tissues of Anguilla anguilla in response to the sea water environment
The aim of this study was to use a microarray approach to screen the major osmoregulatory tissues of the eel for changes in gene expression as fish acclimate to the SW environment. The other species (few clones) were used to validate the specificity of arrays hybridizations : Of the 6144 clones sp...
ORGANISM(S): Anguilla anguilla 
2008-04-19 | E-MAXD-24 | biostudies-arrayexpress
UnknownMutation of the regulator of G protein signaling Crg1 increases virulence in Cryptococcus neoformans.
Not available
S-EPMC500888 | biostudies-literature
TranscriptomicsAffymetrix SNP 6.0 data for individuals with Trisomy 21 or Down syndrome
Individuals with Down syndrome (DS) are at an increased risk for developing congenital heart defects especially atrioventricular septal defects (AVSD). Our goal was to identify the contribution of copy number variants (CNV) to DS-associated AVSD. We used the Affymetrix SNP 6.0 genotyping platform to...
ORGANISM(S): Homo sapiens 
2014-10-24 | E-GEOD-60607 | biostudies-arrayexpress
TranscriptomicsUGE and UGM Reveal Novel Signaling Pathways and Ligand-Receptor Interactions in the Primitive Prostate Stem Cell Niche
We isolated fetal murine urogenital sinus epithelium and urogenital sinus mesenchyme and determined their global gene expression profiles to define their differentially expressed regulators. To distinguish gene expression patterns that are shared by other developing epithelial/mesenchymal compartmen...
ORGANISM(S): Mus musculus 
2010-08-29 | E-GEOD-17797 | biostudies-arrayexpress
UnknownSignificant gene content variation characterizes the genomes of inbred mouse strains.
Not available
S-EPMC2099583 | biostudies-literature
UnknownGenome-wide study of gene-by-sex interactions identifies risks for cleft palate.
Not available
S-EPMC12087800 | biostudies-literature
TranscriptomicsMolecular Signatures of Fetal and Adult Prostate Stem Cells
The global gene expression profiles of adult and fetal murine prostate stem cells were determined to define common and unique regulators whose misexpression might play a role in the development of prostate cancer. A distinctive core of transcriptional regulators common to both fetal and adult primit...
ORGANISM(S): Mus musculus 
2009-04-29 | E-GEOD-15580 | biostudies-arrayexpress
UnknownHuman T cell leukemia virus type I tax-induced IκB-ζ modulates tax-dependent and tax-independent gene expression in T cells.
Not available
S-EPMC3769889 | biostudies-literature
UnknownCopy number variation in the mouse genome: implications for the mouse as a model organism for human disease.
Not available
S-EPMC2920193 | biostudies-literature
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