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GenomicsLoss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death
Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death
PRJNA849237 | ENA
TranscriptomicsLoss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death
Sudden cardiac death (SCD) in patients with heart failure (HF) is allied with an imbalance in reduction-oxidation (redox) signaling in cardiomyocytes; however, the basic pathways and mechanisms governing redox homeostasis in cardiomyocytes are not fully understood. Here, we show that cytochrome b5 r...
ORGANISM(S): Mus musculus 
2023-06-14 | GSE206121 | GEO
GenomicsGene expression profiling by adenoviral CYB5R3 overexpression in non-small cell lung cancer (NSCLC) cell line, NCI-H1299
Gene expression profiling by adenoviral CYB5R3 overexpression in non-small cell lung cancer (NSCLC) cell line, NCI-H1299
PRJNA954031 | ENA
TranscriptomicsGene expression profiling by adenoviral CYB5R3 overexpression in non-small cell lung cancer (NSCLC) cell line, NCI-H1299
To investigate the tumor suppressor roleof CYB5R3 in lung cancer, we infected with adenoviral empty vector (EV) or CYB5R3 in NCI-H1299 cells.
ORGANISM(S): Homo sapiens 
2024-04-20 | GSE229344 | GEO
UnknownThe UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.
Not available
S-EPMC9772183 | biostudies-literature
UnknownCyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure.
Not available
S-EPMC7031142 | biostudies-literature
UnknownCooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation.
Not available
S-EPMC8577475 | biostudies-literature
UnknownLoss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death.
Not available
S-EPMC9479700 | biostudies-literature
UnknownGGPP depletion initiates metaflammation through disequilibrating CYB5R3-dependent eicosanoid metabolism.
Not available
S-EPMC7681012 | biostudies-literature
UnknownEndothelial CYB5R3 couples store-operated calcium entry to TRPV2 activation and vascular fitness.
Not available
S-EPMC12632602 | biostudies-literature
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