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GenomicsTotal RNA-seq using mouse tissues from Cyp2e1 +/+ mice upon pair-fed, Cyp2e1 +/+ mice upon EtOH-fed, Cyp2e1 -/- mice upon pair-fed, and Cyp2e1 -/- mice upon EtOH fed.
Total RNA-seq using mouse tissues from Cyp2e1 +/+ mice upon pair-fed, Cyp2e1 +/+ mice upon EtOH-fed, Cyp2e1 -/- mice upon pair-fed, and Cyp2e1 -/- mice upon EtOH fed.
PRJNA850373 | ENA
GenomicsCYP2E1 TB study
CYP2E1 gene sequencing data for the drug-susceptible TB study sample set (n = 34)
PRJEB69677 | ENA
TranscriptomicsTotal RNA-seq using mouse tissues from Cyp2e1 +/+ mice upon pair-fed, Cyp2e1 +/+ mice upon EtOH-fed, Cyp2e1 -/- mice upon pair-fed, and Cyp2e1 -/- mice upon EtOH fed.
To investigate the effect of Cyp2e1 and EtOH on mRNA expression in mouse tissues, we profiled total RNA expression using mouse tissues from Cyp2e1 -/- mice and Cyp2e1 +/+ mice upon EtOH fed mice compared to control. We compare the expression level of RNA and profile circular RNA expression using cir...
ORGANISM(S): Mus musculus 
2024-06-30 | GSE206348 | GEO
GenomicsCrosstalk between CYP2E1 and PPARα substrates and agonists modulate adipose browning and obesity
Crosstalk between CYP2E1 and PPARα substrates and agonists modulate adipose browning and obesity
PRJNA798014 | ENA
GenomicsQ11, a CYP2E1 inhibitor, exerts anti-hepatocellular carcinoma effect by inhibiting M2 macrophage polarization
Q11, a CYP2E1 inhibitor, exerts anti-hepatocellular carcinoma effect by inhibiting M2 macrophage polarization
PRJNA1190985 | ENA
TranscriptomicsQ11, a CYP2E1 inhibitor, exerts anti-hepatocellular carcinoma effect by inhibiting M2 macrophage polarization
Despite significant advancements in cancer immunotherapy, many patients continue to respond poorly. Novel therapeutic strategies and drugs are urgently needed. Here, we found that CYP2E1 is significantly upregulated in M2 macrophages. The CYP2E1 inhibitor, Q11, could inhibit M2 macrophage polarizati...
ORGANISM(S): Mus musculus 
2024-12-26 | GSE282907 | GEO
UnknownCYP2E1 in 1,4-dioxane metabolism and liver toxicity: insights from CYP2E1 knockout mice study.
Not available
S-EPMC11500436 | biostudies-literature
TranscriptomicsCrosstalk between CYP2E1 and PPARα substrates and agonists modulate adipose browning and obesity
We report the discrepancy of hepatic mRNA expression in Cyp2e1 widetype and knockout mice by application of RNA-seq technology.
ORGANISM(S): Mus musculus 
2022-06-01 | GSE193796 | GEO
TranscriptomicsTranscriptome profiling of normal and CYP2E1 knockdown human neural progenitor cells
The objective of the study was to examine changes in gene expression induced by CYP2E1 knockdown in neural progenitor cells.There were 6samples in total.Samples shs_1, shs_2, and shs_3 are the control group, and shCYP2E1_1, shCYP2E1_2, and shCYP2E1_3 are the CYP2E1 knockdown group.Neural progenitor ...
ORGANISM(S): Homo sapiens 
2025-08-31 | GSE278691 | GEO
UnknownCYP2E1 metabolism of styrene involves allostery.
Not available
S-EPMC3463823 | biostudies-literature
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