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ProteomicsMapping of phosphorylation target sites of obscurin-kin 1 within the cytoplasmic domain of N-cadherin by LC-MS/MS
To test our hypothesis that obscurin-kin1 modulates, at least in part, the mechanochemical coupling of cardiomyocytes via phosphorylation of N-cadherin, which has been shown to play a pivotal role in these processes, we set forth to identify the potential phosphorylation target sites of obscurin-kin...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-23 | PXD031003 | Pride
Cytoplasmic domain of n-cadherin Obscurin kinase 1 Ser phosphorylation Lc-ms/ms 
UnknownDeletion of the cytoplasmic domain of N-cadherin reduces, but does not eliminate, traction force-transmission.
Not available
S-EPMC5030185 | biostudies-literature
UnknownThe nonreceptor protein tyrosine phosphatase PTP1B binds to the cytoplasmic domain of N-cadherin and regulates the cadherin-actin linkage.
Not available
S-EPMC2132848 | biostudies-literature
UnknownThe N-cadherin cytoplasmic domain confers anchorage-independent growth and the loss of contact inhibition.
Not available
S-EPMC4612716 | biostudies-literature
UnknownThe variable transmembrane domain of Drosophila N-cadherin regulates adhesive activity.
Not available
S-EPMC1592838 | biostudies-literature
TranscriptomicsRNA-Seq profiling of single bovine oocyte transcript abundance and its modulation by cytoplasmic polyadenylation
Polyadenylated RNA from individual germinal vesicle and metaphase II ooyctes was amplified and processed for Illumina sequencing. Increases in polyadenylated transcript abundance were observed and are likely due to cytoplasmic polyadenylation. Transcriptomic analysis of GV and MII bovine oocytes.
ORGANISM(S): Bos taurus 
2015-07-08 | E-GEOD-61717 | biostudies-arrayexpress
UnknownInvolvement of Src family kinases in N-cadherin phosphorylation and beta-catenin dissociation during transendothelial migration of melanoma cells.
Not available
S-EPMC1382315 | biostudies-literature
UnknownEssential role of obscurin kinase-1 in cardiomyocyte coupling via N-cadherin phosphorylation.
Not available
S-EPMC10967385 | biostudies-literature
UnknownN-terminal 1-54 amino acid sequence and Armadillo repeat domain are indispensable for P120-catenin isoform 1A in regulating E-cadherin.
Not available
S-EPMC3353978 | biostudies-literature
UnknownN-cadherin regulates primary motor axon growth and branching during zebrafish embryonic development.
Not available
S-EPMC3648643 | biostudies-literature
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