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TranscriptomicsGPM6B regulates osteoblast differentiation and induction of mineralization by controlling cytoskeleton and matrix vesicle release.
Analysis of GPM6B silenced osteogenic hMSC at gene expression level. Analysis is showing significant changes in genes involved in cytoskeleton organization and biogenesis. Immunocytochemistry confirms changed distribution of actin filaments and change in shape and in size of focal adhesions upon GP...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-26004 | biostudies-arrayexpress
GenomicsPTBP1 mediates Sertoli cell actin cytoskeleton organization through regulating alternative splicing of actin regulators
PTBP1 mediates Sertoli cell actin cytoskeleton organization through regulating alternative splicing of actin regulators
PRJNA1113639 | ENA
ProteomicsSeptin 7 Interacts With Numb To Preserve Sarcomere Structural Organization And Muscle Contractile Function
Here, we investigated mechanisms by which aging-related reductions of the levels of Numb in skeletal muscle fibers contribute to loss of muscle strength and power, two critical features of sarcopenia. Numb is an adaptor protein best known for its critical roles in development including asymmetric ce...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-04-28 | MSV000089327 | MassIVE
UnknownSingle molecule visualization of tropomyosin isoform organization in the mammalian actin cytoskeleton.
Not available
S-EPMC11748362 | biostudies-literature
UnknownArabidopsis calcium-dependent protein kinase 3 regulates actin cytoskeleton organization and immunity.
Not available
S-EPMC7718926 | biostudies-literature
TranscriptomicsFunctional Comparison of Chronological and In Vitro Aging: Differential Role of the Cytoskeleton and Mitochondria in Mesenchymal Stromal Cells
Mesenchymal stromal cells (MSCs) are of high relevance for the regeneration of mesenchymal tissues such as bone and cartilage. The promising role of MSCs in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor age, t...
ORGANISM(S): Rattus norvegicus 
2013-01-05 | E-GEOD-36596 | biostudies-arrayexpress
UnknownTubulin Cytoskeleton Organization in Cells of Determinate Nodules.
Not available
S-EPMC9087740 | biostudies-literature
UnknownRegulation of the actin cytoskeleton organization in yeast by a novel serine/threonine kinase Prk1p.
Not available
S-EPMC2148122 | biostudies-literature
TranscriptomicsThe histone demethylase PHF8 is essential for cytoskeleton dynamics
PHF8 is a histone demethylase associated with X-linked mental retardation (XLMR). It has been described as a transcriptional coactivator involved in cell cycle progression, but its physiological role is still poorly understood. Here we show that PHF8 controls the expression of genes involved in cell...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-38175 | biostudies-arrayexpress
UnknownMicroenvironmental stiffness mediates cytoskeleton re-organization in chondrocytes through laminin-FAK mechanotransduction.
Not available
S-EPMC8917190 | biostudies-literature
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