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TranscriptomicsTranscription profiling of human CD8 T lymphocytes from two healthy donors transduced with hTERT
Expression in GFP vs. GFP/hTERT transduced CD8 T Lymphocytes from Healty Donors (HD) 1 and 2 at early and late passages. Using CD8+ T lymphocyte clones over-expressing telomerase weinvestigated the molecular mechanisms that regulate T cell proliferation. Transduction and subcloning procedures were p...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5144 | biostudies-arrayexpress
TranscriptomicsModelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 [RNA-seq]
Down syndrome (trisomy 21) is the most common viable chromosomal disorder with intellectual impairment and several other developmental abnormalities. Here, we report the generation and characterization of induced pluripotent stem cells (iPSCs) derived from monozygotic twins discordant for trisomy 21...
ORGANISM(S): Homo sapiens 
2013-12-01 | E-GEOD-52249 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD* T lymphocytes overexpressing hTERT
Using CD8+ T lymphocyte clones over-expressing telomerase weinvestigated the molecular mechanisms that regulate T cell proliferation. Transduction and subcloning procedures were performed on CD8 + naive T-cell clones isolated from two different healthy individuals aged between 30 to 35 years (HD1 a...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5143 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of gulahuman CD8 T lyphocytes overexpressing hTERT to investigate regulation of profileration
Using CD8+ T lymphocyte clones over-expressing telomerase weinvestigated the molecular mechanisms that regulate T cell proliferation. Transduction and subcloning procedures were performed on CD8 + naive T-cell clones isolated from two different healthy individuals aged between 30 to 35 years (HD1 a...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5142 | biostudies-arrayexpress
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