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Proteomics[HPP-2.0] Phosphoproteome Profiling of uEV Reveals p-AQP2 and p-GSK3β as Potential Markers for Diabetic Nephropathy
We used ultra-high-sensitivity quantitative phosphoproteomics to identify phosphoproteins in urinary extracellular vesicles (uEVs) as potential biomarkers of DN. We detected 233 phosphopeptides within the uEVs, with 47 phosphoproteins exhibiting significant alterations in patients with DN compared t...
ORGANISM(S): Homo Sapiens 
2024-02-01 | PXD049107 |
Proteomics[HPP-2.0] Phosphoproteome Profiling of uEV Reveals p-AQP2 and p-GSK3β as Potential Markers for Diabetic Nephropathy-2
We used ultra-high-sensitivity quantitative phosphoproteomics to identify phosphoproteins in urinary extracellular vesicles (uEVs) as potential biomarkers of DN. We detected 233 phosphopeptides within the uEVs, with 47 phosphoproteins exhibiting significant alterations in patients with DN compared t...
ORGANISM(S): Homo Sapiens Bos Taurus 
2024-02-20 | PXD049714 |
UnknownYu ping feng san for pediatric allergic rhinitis: A systematic review and meta-analysis of randomized controlled trials.
Not available
S-EPMC8021384 | biostudies-literature
TranscriptomicsMIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes
The piRNA machinery is known for its role in mediating epigenetic silencing of transposons. Recent studies suggest that this function also involves piRNA-guided cleavage of transposon-derived transcripts. As many piRNAs also appear to have the capacity to target diverse mRNAs, this raises the intrig...
ORGANISM(S): Mus musculus 
2015-04-09 | E-GEOD-67683 | biostudies-arrayexpress
MetabolomicsParabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and reduces ...
2023-11-01 | MTBLS7943 | MetaboLights
MetabolomicsLow chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
Dysregulated extravillous trophoblast invasion and proliferation are known to increase the risk of recurrent spontaneous abortion (RSA); however, the underlying mechanism remains unclear. Herein, in our retrospective observational case-control study we show that villous samples from RSA patients, co...
2021-10-06 | MTBLS2148 | MetaboLights
UnknownArtificial intelligence with a deep learning network for the quantification and distinction of functional adrenal tumors based on contrast-enhanced CT images.
Not available
S-EPMC10102777 | biostudies-literature
UnknownThe Gustavus Gene Can Regulate the Fecundity of the Green Peach Aphid, Myzus persicae (Sulzer).
Not available
S-EPMC7835840 | biostudies-literature
ProteomicsQuantitative Proteomics Reveals Dormancy Related Proteins Mediated Attenuation Program in Mycobacterium Strain
To better understand the virulence difference among different MTB strains and identify new targets for therapeutic intervention under hypoxia condition, we compared the global protein expression at the protein level by quantitative proteomics among H37Rv, H37Ra and BCG.
ORGANISM(S): Mycobacterium tuberculosis Mycobacterium tuberculosis complex 
2022-04-01 | PXD017174 | Pride
Mycobacterium tuberculosis Tmt Virulence，quantitative proteomic 
UnknownClinical characteristics and treatment outcomes of SARS-CoV-2 delta variant outbreak, Pingtung, Taiwan, June 2021.
Not available
S-EPMC8761556 | biostudies-literature
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